Anti-TERE1 Antibody

Name: Anti-TERE1 Antibody
Brand: PhosphoSolutions
SKU: 24378
Price: 456.0 USD
Availability: InStock

Our TERE1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human TERE1 and is antigen affinity purified. It is great for use in WB.

Western Blot of 30 ug of normal human bladder mucosa (lane 1) and urothelial carcinoma (lane 2) showing specific immunolabeling of TERE1.

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24378

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TERE1

Scientific Background

A novel gene designated TERE1, has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified by loss of heterozygosity studies as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

UBIAD1

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human TERE1 protein

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N-terminal region of the 37 kDa human TERE1 protein. This sequence is 85% identical in mouse and rat.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

SCCD; UBIAD1; ubiA prenyltransferase domain-containing protein 1; transitional epithelia response protein; transitional epithelial response protein 1

UniProt ID

Q9Y5Z9
UniProt Summary: Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.

NCBI Gene ID

29914

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Blue Ice

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Anti-TERE1 Antibody

SKU: 24378

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