Anti-Synuclein, pan Antibody
Our Anti-Pan-synuclein rabbit polyclonal primary antibody detects human and rat Pan-synuclein, and is whole serum. It is validated for use in IHC-Frozen, WB.
SKU: R-060-100
Product Details
Pan-synuclein
Detects human alpha-, beta-, and gamma synuclein proteins. A family of homologous proteins known as alpha-, beta-, and gamma-synuclein are abundantly expressed in brain, especially in the presynaptic terminal of neurons. Although the precise function of these proteins remains unknown, alpha-synuclein has been implicated in synaptic plasticity associated with avian song learning as well as in the pathogenesis of Parkinson's disease (PD), dementia with LBs (DLB), some forms of Alzheimer's disease (AD), and multiple system atrophy (MSA).
Whole serum
Polyclonal
Mixed
IHC, WB
Rabbit
A synthetic peptide (AKEGVVAAAEKTKQGV) as a consensus part of human alpha-, beta-, and gamma synuclein proteins conjugated to diphteria toxoid has been used as the immunogen.
Human
Human, Rat
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Lyophilized
WB: 1:1000
IHC: 1:1000
IHC: 1:1000
Unconjugated
Overlap specific immunohistochemical staining of alpha-, beta- and gamma synucleins This antiserum recognizes human and rat alpha-, beta- and gamma synucleins.
For research use only.
United States
12 months after date of receipt (unopened vial).
25°C (ambient)