Anti-SynDIG1/Tmem90b Antibody (L42/17)

Name: Anti-SynDIG1/Tmem90b Antibody
Brand: NeuroMab
SKU: 75-251
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

3 Citations

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L42/17

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Syndig1 Tmem90b

Molecular Weight

36 kDa

Go to Full Product Details

Adult rat brain membrane immunoblot.

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-SynDIG1/Tmem90b Antibody

Product Details

Target

SynDIG1/Tmem90b

Target Description

Transmembrane Protein 90B or Synapse Differentiation Inducing 1 (SynDIG1/Tmem90b) is encoded by the gene SYNDIG1 and a member of the interferon-induced transmembrane family of proteins. (IFITM). SynDIG1 is thought to regulate AMPA receptors and be involved in postsynaptic development and maturation. SynDIG1 is expressed in the brain at excitatory synapses and postsynaptic cells. Diseases associated with this gene include Episodic Kinesigenic Dyskinesia and Visual Epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L42/17

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

Syndig1 Tmem90b

Molecular Weight

36 kDa

Antigen

Fusion protein amino acids 1-183 (cytoplasmic N-terminus) of mouse SynDIG1 (accession number A2ANU3) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10999753

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Synapse differentiation-inducing gene protein 1 (SynDIG1) (Dispanin subfamily C member 2) (DSPC2) (Transmembrane protein 90B)

UniProt Details

UniProt (Human): Q9H7V2
UniProt (Immunogen Species): A2ANU3

Kirk LM, Ti SW, Bishop HI, Orozco-Llamas M, Pham M, Trimmer JS, Díaz E. (2016), 'Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain..' J Comp Neurol.. 10.1002/cne.23945.
Sumioka A, Brown TE, Kato AS, Bredt DS, Kauer JA, Tomita S. (2011), 'PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity..' Nat Neurosci.. 10.1038/nn.2952.
Kalashnikova E, Lorca RA, Kaur I, Barisone GA, Li B, Ishimaru T, Trimmer JS, Mohapatra DP, Díaz E. (2010), 'SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development..' Neuron.. 10.1016/j.neuron.2009.12.021.

Recover password

Create my account

Anti-SynDIG1/Tmem90b Antibody (L42/17)

Available Conjugates

Anti-SynDIG1/Tmem90b Antibody
SKU: 75-251

Bulk Order Anti-SynDIG1/Tmem90b Antibody

Product Details

Related Products

Recently Viewed

Anti-SynDIG1/Tmem90b Antibody (L42/17)

Available Conjugates

Anti-SynDIG1/Tmem90b Antibody SKU: 75-251

Bulk Order Anti-SynDIG1/Tmem90b Antibody

Product Details

Anti-SynDIG1/Tmem90b Antibody
SKU: 75-251