Anti-SynDIG1/Tmem90b Antibody (L42/17)

Name: Anti-SynDIG1/Tmem90b Antibody
Brand: NeuroMab
SKU: 75-251
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

3 Citations

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L42/17

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

Syndig1 Tmem90b

Molecular Weight

36 kDa

Go to Full Product Details

Adult rat brain membrane immunoblot.

Volume: 100 µL

Variant

Price:

$308

Quantity:

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Product Details

Target

SynDIG1/Tmem90b

Target Description

Transmembrane Protein 90B or Synapse Differentiation Inducing 1 (SynDIG1/Tmem90b) is encoded by the gene SYNDIG1 and a member of the interferon-induced transmembrane family of proteins. (IFITM). SynDIG1 is thought to regulate AMPA receptors and be involved in postsynaptic development and maturation. SynDIG1 is expressed in the brain at excitatory synapses and postsynaptic cells. Diseases associated with this gene include Episodic Kinesigenic Dyskinesia and Visual Epilepsy.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L42/17

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

Syndig1 Tmem90b

Molecular Weight

36 kDa

Antigen

Fusion protein amino acids 1-183 (cytoplasmic N-terminus) of mouse SynDIG1 (also known as Synapse differentiation-inducing gene protein 1, Dispanin subfamily C member 2, Transmembrane protein 90B, DSPC2, Tmem90b and C20orf39, accession number A2ANU3); Rat: 97% identity (179/183 amino acids identical); Human: 91% identity (167/183 amino acids identical); 50% identity with SynDIG1L/SynDIG2/Capucin/Tmem90a

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10999753

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Synapse differentiation-inducing gene protein 1 (SynDIG1) (Dispanin subfamily C member 2) (DSPC2) (Transmembrane protein 90B)

UniProt Details

UniProt (Human): Q9H7V2
UniProt (Immunogen Species): A2ANU3

Kirk LM, Ti SW, Bishop HI, Orozco-Llamas M, Pham M, Trimmer JS, Díaz E. (2016), 'Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain..' J Comp Neurol.. 10.1002/cne.23945.
Sumioka A, Brown TE, Kato AS, Bredt DS, Kauer JA, Tomita S. (2011), 'PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity..' Nat Neurosci.. 10.1038/nn.2952.
Kalashnikova E, Lorca RA, Kaur I, Barisone GA, Li B, Ishimaru T, Trimmer JS, Mohapatra DP, Díaz E. (2010), 'SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development..' Neuron.. 10.1016/j.neuron.2009.12.021.

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Anti-SynDIG1/Tmem90b Antibody (L42/17)

Anti-SynDIG1/Tmem90b Antibody
SKU: 75-251

Bulk Order Anti-SynDIG1/Tmem90b Antibody

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Anti-SynDIG1/Tmem90b Antibody (L42/17)

Anti-SynDIG1/Tmem90b Antibody SKU: 75-251

Bulk Order Anti-SynDIG1/Tmem90b Antibody

Product Details

Anti-SynDIG1/Tmem90b Antibody
SKU: 75-251