Anti-SynDIG1/Tmem90b Antibody (L42/17)

Name: Anti-SynDIG1/Tmem90b Antibody
Brand: NeuroMab
SKU: 75-251
Price: 337.0 USD
Availability: InStock

Our mouse SynDIG1/Tmem90b monoclonal antibody from NeuroMab is produced in-house from clone L42/17. It detects human, mouse, and rat SynDIG1/Tmem90b and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult rat brain membrane immunoblot.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-251

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

SynDIG1/Tmem90b

Scientific Background

Transmembrane Protein 90B or Synapse Differentiation Inducing 1 (SynDIG1/Tmem90b) is encoded by the gene SYNDIG1 and a member of the interferon-induced transmembrane family of proteins. (IFITM). SynDIG1 is thought to regulate AMPA receptors and be involved in postsynaptic development and maturation. SynDIG1 is expressed in the brain at excitatory synapses and postsynaptic cells. Diseases associated with this gene include Episodic Kinesigenic Dyskinesia and Visual Epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L42/17

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Syndig1 Tmem90b

Molecular Weight

36 kDa

Immunogen

Fusion protein amino acids 1-183 (cytoplasmic N-terminus) of mouse SynDIG1 (accession number A2ANU3) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10999753

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

AW123113; Synapse differentiation-inducing gene protein 1; Gm14134; SynDIG1; H2C20orf39; Dispanin subfamily C member 2; Tmem90b; DSPC2; Transmembrane protein 90B

UniProt ID

A2ANU3
UniProt Summary: May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.

NCBI Gene ID

433485

Shipping

Shipped on ice packs

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Anti-SynDIG1/Tmem90b Antibody (L42/17)

SKU: 75-251

Product Details

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