Anti-SUR1 and SUR2B Antibody (N323A/31)

Name: Anti-SUR1 and SUR2B Antibody
Brand: NeuroMab
SKU: 75-298
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, WB

Host Species

Mouse

Gene Name

Abcc8 Sur Sur1 Abcc9 Sur2

Molecular Weight

175 kDa (and smaller fragments likely due to proteolytic cleavage)

Go to Full Product Details

Immunoblot versus extracts of heart tissue from WT and SUR2 KO mice probed with N323A/31 TC supe. Data courtesy of William Coetzee and Margaret Rice, New York University SOM.

Product Details

Target

ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

Target Description

SUR1 and SUR2B are members of the ATP binding cassette transporter subfamily C. These proteins combine with KCNJ8(Kir6.1) or KCNJ11(Kir6.2) to form K+ATP channels and are involved in their regulation and activation.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N323A/31

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Abcc8 Sur Sur1 Abcc9 Sur2

Molecular Weight

175 kDa (and smaller fragments likely due to proteolytic cleavage)

Antigen

Fusion protein amino acids 1503-1545 (VHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM, cytoplasmic C-terminus) of rat SUR2B (also known as Sulfonylurea receptor 2B, ATP-binding cassette transporter subfamily C member 9B and Abcc9B, accession number Q63563-2); Mouse: 100% identity (43/43 amino acids identical); Human: 97% identity (42/43 amino acids identical); 75% identity with SUR1

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315926

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Cross-reacts with SUR1

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

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Anti-SUR1 and SUR2B Antibody (N323A/31)

Anti-SUR1 and SUR2B Antibody
SKU: 75-298

Product Details

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Anti-SUR1 and SUR2B Antibody (N323A/31)

Anti-SUR1 and SUR2B Antibody SKU: 75-298

Product Details

Anti-SUR1 and SUR2B Antibody
SKU: 75-298