Anti-Snapin/SNAPAP Antibody (L8/15)

Name: Anti-Snapin/SNAPAP Antibody
Brand: NeuroMab
SKU: 75-045
Price: 329.0 USD
Availability: InStock

2 Citations

Our Anti-Snapin/SNAPAP mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L8/15. It detects human, mouse, and rat Snapin/SNAPAP, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Immunoblot on adult rat brain membrane (RBM) and samples from transfected COS cells.

Adult rat hippocampus immunohistochemistry.

Immunoblot on adult rat brain membrane (RBM) and samples from transfected COS cells.

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-045

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Snapin/SNAPAP

Target Description

SNARE-associated protein Snapin, SNAP Associated Protein or Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 7 (BLOC-1 Subunit 7) is encoded by the gene SNAPIN. Snapin is a member of the BLOC-1 complex, which is involved in the protein-sorting, membrane biogenesis, and vesicular trafficking. Snapin is required for vesicle docking and fusion and regulates neurotransmitter release. Snapin is expressed in many tissues including heart, brain, testis, kidney and liver. Diseases associated with this gene include Hermansky-Pudlak Syndrome and Tricuspid Valve Stenosis.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L8/15

Isotype

IgG1

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

SNAPIN BLOC1S7 SNAP25BP SNAPAP

Molecular Weight

20 kDa

Antigen

Synthetic peptide of amino acids 115-136 of human snapin (KETARRRAMLDSGIYPPGSPGK; accession number Q95295)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2255078

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

SNARE-associated protein Snapin (Biogenesis of lysosome-related organelles complex 1 subunit 7) (BLOC-1 subunit 7) (Synaptosomal-associated protein 25-binding protein) (SNAP-associated protein)

UniProt ID

O95295

Product Specific References for Applications and Species

Immunoprecipitation: Human
Western Blot: Mouse

Immunoprecipitation: Human
PMID	Dilution	Publication
24118254	not listed	Makani, V., et al. 2013. Annexin A1 complex mediates oxytocin vesicle transport.. J Neuroendocrinol., 1241-1254.

Western Blot: Mouse
PMID	Dilution	Publication
27929705	10ug	Shi, B.O., et al. 2017. SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Autophagy, 285-301.

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Anti-Snapin/SNAPAP Antibody (L8/15)

SKU: 75-045

Product Details

Product Specific References for Applications and Species

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