Anti-Shank1 And Shank3 Antibody (N367/51)

Name: Anti-Shank1 And Shank3 Antibody
Brand: NeuroMab
SKU: 75-343
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

This antibody recognizes an epitope found in SH3 and multiple ankyrin repeat domains protein 1 (Shank 1) and SH3 and multiple ankyrin repeat domains protein 3 (Shank3).

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N367/51

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Shank1 Shank3 Prosap2

Molecular Weight

190 kDa

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Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Shank1, Shank2, Shank3 or untagged Kv2.1 plasmid and probed with N367/51 (left) or N23B/49 (right) TC supe.

Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon) SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)

Target Description

Shank proteins act as scaffold proteins anchoring and connecting membrane bound receptors and other proteins to the cytoskeleton in neurons to enable cell signaling.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N367/51

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Shank1 Shank3 Prosap2

Molecular Weight

190 kDa

Antigen

Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (also known as SH3 and multiple ankyrin repeat domains protein 3, Proline-rich synapse-associated protein 2, ProSAP2, PSAP2, SPANK-2 and Kiaa1650, accession number Q9JLU4); Mouse: 100% identity (89/89 amino acids identical); Human: 97% identity (87/89 amino acids identical); ~70% identity with Shank1 and Shank2

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315919

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Cross-reacts with Shank1 Does not cross-react with Shank2

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

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Anti-Shank1 And Shank3 Antibody (N367/51)

This antibody recognizes an epitope found in SH3 and multiple ankyrin repeat domains protein 1 (Shank 1) and SH3 and multiple ankyrin repeat domains protein 3 (Shank3).

Anti-Shank1 And Shank3 Antibody
SKU: 75-343

Bulk Order Anti-Shank1 And Shank3 Antibody

Product Details

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Anti-Shank1 And Shank3 Antibody (N367/51)

This antibody recognizes an epitope found in SH3 and multiple ankyrin repeat domains protein 1 (Shank 1) and SH3 and multiple ankyrin repeat domains protein 3 (Shank3).

Anti-Shank1 And Shank3 Antibody SKU: 75-343

Bulk Order Anti-Shank1 And Shank3 Antibody

Product Details

Anti-Shank1 And Shank3 Antibody
SKU: 75-343