Anti-SH3GL1/Endophilin A2 Antibody (K51/1)

Name: Anti-SH3GL1/Endophilin A2 Antibody
Brand: NeuroMab
SKU: 75-049
Price: 319.0 USD
Availability: InStock

3 Citations

Our Anti-SH3GL1/Endophilin A2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K51/1. It detects mouse and rat SH3GL1/Endophilin A2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat hippocampus immunohistochemistry.

Adult rat whole brain immunohistochemistry.

$Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with K51/1 (left) or N52A/42 (right) TC supe.$

Adult rat hippocampus immunohistochemistry.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-049

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

SH3GL1/Endophilin A2

Target Description

Endophilin-A2, SH3 domain protein 2B or SH3 Domain-Containing GRB2-Like Protein 1 is encoded by the gene Sh3gl1 and a member of the endophilin family of Src homology 3 domain-containing proteins. Endophilin-A2 is involved in endocytosis and is thought to recruit other proteins to the membrane. Endophilin-A2 may also play a role in the cell cycle. Endophilin-A2 is expressed ubiquitously in tissues. Diseases associated with SH3GL1 include Leukemia and Acute Myeloid Leukemia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K51/1

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Sh3gl1 Sh3p8

Molecular Weight

43 kDa

Antigen

Synthetic peptide amino acids 287-302 of rat SH3GL1 (accession number AAH70893)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2189399

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) (SH3p8)

UniProt Details

UniProt (Human): Q99961
UniProt (Immunogen Species): O35964

Product Specific References for Applications and Species

Immunohistochemistry: Mouse | Rat

Immunohistochemistry: Mouse
PMID	Dilution	Publication
19156860	not listed	Ogawa, Y., et al. 2009. Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.. Journal of Neuroscience Research, 3502-3510.
17610815	not listed	Micheva, K.D., et al. 2007. Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits.. Neuron, 25-36.

Immunohistochemistry: Rat
PMID	Dilution	Publication
19156860	not listed	Ogawa, Y., et al. 2009. Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.. Journal of Neuroscience Research, 3502-3510.

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Anti-SH3GL1/Endophilin A2 Antibody (K51/1)

SKU: 75-049

Product Details

Product Specific References for Applications and Species

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