Anti-SARS-CoV-2 S-Protein ACE2 Binding Domain Antibody (2G1)
Our SARS-CoV-2 S-Protein ACE2 Binding Domain primary antibody from PhosphoSolutions is mouse monoclonal. It detects SARS-CoV-2 S-Protein ACE2 Binding Domain and is Protein G purified. It is great for use in WB, ICC.
SKU: CoV2-2G1
Product Details
SARS-CoV-2 S-Protein ACE2 Binding Domain
The novel SARS-coronavirus 2 (SARS-CoV-2) which causes the disease COVID-19 has been shown to utilize the SARS-CoV receptor ACE2 for entry into human cells (Hoffman, M. et al., Cell 2020). The entry of a coronavirus into host cells is mediated by the viral surface-anchored transmembrane spike (S) glycoprotein which is composed of two functional subunits, S1 which binds the receptor and S2 which fuses the membrane (Walls, AC et.al., Cell 2020). S1 contains a receptor-binding domain (RBD) which specifically recognizes ACE2 as its receptor (Wan, Y. et al., 2020).
Protein G Purified
Monoclonal
2G1
IgG1
ICC, WB
Mouse
S
25 kDa or 142 kDa full-length
Recombinant SARS-CoV-2 S-Protein construct containing the ACE2 binding domain expressed in and purified from E. coli.
SARS-CoV2
AB_2868397
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Liquid
Protein G purified culture supernatant.
PBS + 50% glycerol and 5 mm NaN3
WB: 1:2000
ICC: 1:1000
ICC: 1:1000
Unconjugated
Specific for the ~25 kDa ACE2 binding domain construct of SARS-CoV-2 S protein. Full-length CoV-2 S protein is ~142 kDa.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
Blue Ice
UniProt (Immunogen Species): P0DTC2
Product Specific Protocols
- Western Blot Protocol: Download