Anti-SAPAP1/2 Antibody (N238/31)
Our Anti-SAPAP1/2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/31. It detects human, mouse, and rat SAPAP1/2, and is purified by Protein A chromatography. It is great for use in ICC, WB.
SKU: 75-236
Product Details
SAPAP1/2
SAPAP1 (also known as disks large associated protein 1) and SAPAP2 (also known as disks large associated protein 2) are members of the SAPAP or DLGAP family of proteins. SAPAP proteins function as scaffolding proteins at excitatory synapses. SAPAP proteins interact with PSD95 family and Shank family proteins to anchor/target neurotransmitter receptors and signaling molecules to the postsynaptic membrane of excitatory synapses.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N238/31
IgG1
ICC, WB
Mouse
DLGAP1 DAP1 GKAP DLGAP2 C8orf68 DAP2 ERICH1-AS1
110 kDa (varies due to post-translational modifications)
Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (accession number P97836) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2230571
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Unconjugated
Does not cross-react with other SAPAPs
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Disks large-associated protein 1 (SAPAP1) SAPAP-1 Disks large-associated protein 2 (SAPAP2) SAPAP-2
UniProt (Human): O14490
UniProt (Immunogen Species): P97836
UniProt (Immunogen Species): P97836
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- Lugo JN, Smith GD, Arbuckle EP, White J, Holley AJ, Floruta CM, Ahmed N, Gomez MC, Okonkwo O. (2014), 'Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins..' Frontiers in Molecular Neuroscience. 10.3389/fnmol.2014.00027.
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