SAPAP1 (also known as disks large associated protein 1) and SAPAP2 (also known as disks large associated protein 2) are members of the SAPAP or DLGAP family of proteins. SAPAP proteins function as scaffolding proteins at excitatory synapses. SAPAP proteins interact with PSD95 family and Shank family proteins to anchor/target neurotransmitter receptors and signaling molecules to the postsynaptic membrane of excitatory synapses.
DLGAP1 DAP1 GKAP DLGAP2 C8orf68 DAP2 ERICH1-AS1
110 kDa(varies due to post-translational modifications)
Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (also known as disks largeassociated protein 1, DAP-1, guanylate kinase-associated protein, GKAP, SAP90/PSD-95-associated/binding protein 1 and Dlgap1, accession number P97836); Mouse: 99% identity (200/201 amino acids identical) Human: 99% identity (199/201 amino acids identical) 55-65% identity with other SAPAPs
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with other SAPAPs
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Disks large-associated protein 1 (SAPAP1) SAPAP-1 Disks large-associated protein 2 (SAPAP2) SAPAP-2
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