Rufy3 (RUN And FYVE Domain Containing 3) or rap2 interacting protein x,single axon-related 1 (RIPX) contains a RUN domain and two coiled-coil domains. It is implicated in the formation of a single axon by developing neurons and is thought to play a role in the generation of neuronal polarity formation and axon growth.
Diseases associated with RUFY3 include Gastric Cancer
ICC, IHC, WB
Fusion protein amino acids 370-469 (C-terminus) of mouse Rufy3 (also known as RUN and FYVE domain-containing protein 3, Rap2-interacting protein x, Single axon-regulated protein, Singar, Singar1, KIAA0871, D5Bwg0860e and Ripx, accession number Q9D394); Rat: 100% identity (100/100 amino acids identical); Human: 100% identity (100/100 amino acids identical); <50% identity with Rufy2 and other Rufy proteins
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.