Anti-RGS14 Antibody (N133/21)

Our Anti-RGS14 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N133/21. It is KO validated, detects mouse and rat RGS14, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.



SKU: 75-170

Volume: 100 µL
1-2 business days
Price:
Sale price$374

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
21158412not listedVellano, C.P., et al. 2011. Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.. Biochemistry, 752-62.
Immunocytochemistry: Mouse
PMID Dilution Publication
373030641:500Peng, S, et al. 2023. A New AAV Tool for Highly Preferentially Targeting Hippocampal CA2. Molecular Brain, 50.
21158412not listedVellano, C.P., et al. 2011. Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.. Biochemistry, 752-62.
Immunohistochemistry: Human
PMID Dilution Publication
238177831:500Evans, P.R., et al. 2013. Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.. Journal of Comparative Neurology, 186-203.
21158412not listedVellano, C.P., et al. 2011. Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.. Biochemistry, 752-62.
Immunohistochemistry: Mouse
PMID Dilution Publication
38075021not listedOakley, R, et al. 2024. Imbalanced glucocorticoid and mineralocorticoid stress hormone receptor function has sex-dependent and independent regulatory effects in the mouse hippocampus. Neurobiology of Stress, 100589.
37833914not listedBurke, CT, et al. 2023. EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications. International Journal of Molecular Sciences, .
377975811:400Shih, YT, et al. 2023. An inhibitory circuit-based enhancer of DYRK1A function reverses Dyrk1a-associated impairment in social recognition. Neuron, 3084-3101.e5.
373783391:500Takemoto, M, et al. 2023. Dissection of Insular Cortex Layer 5 Reveals Two Sublayers With Opposing Modulatory Roles in Appetitive Drinking Behavior. iScience, 106985.
373030641:500Peng, S, et al. 2023. A New AAV Tool for Highly Preferentially Targeting Hippocampal CA2. Molecular Brain, 50.
371590951:200Dudek, SM, et al. 2023. Defining Hippocampal Area CA2 in the Fox (Vulpes vulpes) Brain. Hippocampus, 700-711.
370759481:500Harbin, N.H., et al. 2023. RGS14 Limits Seizure-Induced Mitochondrial Oxidative Stress and Pathology in Hippocampus. Neurobiology of Disease, 106128.
369910011:500Cope, E.C., et al. 2023. Activation of the CA2-Ventral CA1 Pathway Reverses Social Discrimination Dysfunction in Shank3B Knockout Mice. Nature Communications, 1750.
369714281:500Samadi, M., et al. 2023. Mechanisms of mGluR-Dependent Plasticity in Hippocampal Area CA2. Hippocampus, .
367625881:500Radzicki, D., et al. 2023. Morphological and Molecular Markers of Mouse Area CA2 Along the Proximodistal and Dorsoventral Hippocampal Axes. Hippocampus, 133-149.
366237611:1000Katsube, S., et al. 2023. The Murine Ortholog of Kaufman Oculocerebrofacial Syndrome Gene Ube3b is Crucial for the Maintenance of the Excitatory Synapses in the Young Adult Stage. Neuroscience Letters, 137059.
363518431:50Kim, S., et al. 2022. Visuosocial Preference Memory, But Not Avoidance Memory, Requires PLCγ1 In The CA2 Hippocampus. Experimental Neurobiology, 332-342.
363099631:500Diethorn, E.J., et al. 2022. Postnatal Development of Hippocampal CA2 Structure and Function During the Emergence of Social Recognition of Peers. Hippocampus, .
35987207not listedWhitebirch, A.C., et al. 2022. Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy. Neuron, .
35180391not listedLopez-Rojas, J., et al. 2022. A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory. Neuron, 44575.
335034211:500Laham, B. J., et al. 2021. Newborn mice form lasting CA2-dependent memories of their mothers. Cell Reports, 108668.
334103991:500Squires, K. E., et al. 2021. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. Journal of Biological Chemistry, 100024.
33077947not listedDonegan, M.L., et al. 2020. Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model. Nature Neuroscience, 1365-75.
316656271:300Domínguez, S., et al. 2019. Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. Cell Reports, 1099-112.e4.
31442405not listedSuh, J., et al. 2019. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell, 1159-1175.
313191671:1000Alexander, G. M., et al. 2019. Modulation of CA2 Neuronal Activity Increases Behavioral Responses to Fear Conditioning in Female Mice. Neurobiology of Learning and Memory, 107044.
311210741:500Tulke, S., et al. 2019. Expression of brain-derived neurotrophic factor and structural plasticity in the dentate gyrus and CA2 region correlate with epileptiform activity. Epilepsia, 1234-7.
309267501:500-1:1000Salib, M., et al. 2019. GABAergic Medial Septal Neurons with Low-Rhythmic Firing Innervating the Dentate Gyrus and Hippocampal Area CA3. Journal of Neuroscience, 4527-49.
308311601:100Takahashi, K., et al. 2019. Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice. Neuropharmacology, 1-14.
307189021:400Besnard, A., et al. 2019. Dorsolateral septum somatostatin interneurons gate mobility to calibrate context-specific behavioral fear responses. Nature Neuroscience, 436-46.
300672881:250Helton, T. D., et al. 2019. Diversity of dendritic morphology and entorhinal cortex synaptic effectiveness in mouse CA2 pyramidal neurons. Hippocampus, 78-92.
305188591:50Leroy, F., et al. 2018. A hippocampal CA2 to lateral septal circuit disinhibits social aggression. Nature, 213-8.
303018991:500Meira, T., et al. 2018. A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics. Nature Communications, 4163.
302938211:100Tirko, N. N., et al. 2018. Oxytocin Transforms Firing Mode of CA2 Hippocampal Neurons. Neuron, 593–608.e3.
295719191:500Kragness, S., et al. 2018. Age-dependent expression pattern in the mammalian brain of a novel, small peptide encoded in the 22q11.2 deletion syndrome region. Gene Expression Patterns, 95-103.
292224691:400Raam, T., et al. 2018. Hippocampal oxytocin receptors are necessary for discrimination of social stimuli. Nature communications, 8(1), pp.1-14.. Nature Communications, 44575.
288562401:10Palacio, S., et al. 2017. Heterogeneity in Kv2 Channel Expression Shapes Action Potential Characteristics and Firing Patterns in CA1 versus CA2 Hippocampal Pyramidal Neurons. eNeuro, ENEURO.0267-17.2017.
288237301:50Leroy, F., et al. 2017. Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory.. Neuron, 1089–1102.e5.
267480911:300Piskorowski, R. A., et al. 2016. Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome. Neuron, 163-76.
264825411:500Häussler, U., et al. 2016. Mossy fiber sprouting and pyramidal cell dispersion in the hippocampal CA2 region in a mouse model of temporal lobe epilepsy. Hippocampus, 577-88.
254467211:1000Llorens-Martín, M., et al. 2015. Novel connection between newborn granule neurons and the hippocampal CA2 field.. Experimental Neurology, 285-92.
245723571:50Hitti, F.L., et al. 2014. The hippocampal CA2 region is essential for social memory.. Nature, 88-92.
243361511:500Kohara, K., et al. 2014. Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits.. Nature Neuroscience, 269-79.
240053071:300Piskorowski, R., et al. 2014. Delta-opioid receptors mediate unique plasticity onto parvalbumin-expressing interneurons in area CA2 of the hippocampus.. Journal of Neuroscience, 14567-78.
238177831:500Evans, P.R., et al. 2013. Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.. Journal of Comparative Neurology, 186-203.
21158412not listedVellano, C.P., et al. 2011. Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.. Biochemistry, 752-62.
20837545not listedLee, S.E., et al. 2010. RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory.. Proceedings of the National Academy of Science of the United States of America, 16994-8.
Immunohistochemistry: Rat
PMID Dilution Publication
349991861:250Park, S.B., et al. 2022. The fasciola cinereum subregion of the hippocampus is important for the acquisition of visual contextual memory. Progress in Neurobiology, 102217.
269342241:400Kay, K., et al. 2016. A hippocampal network for spatial coding during immobility and sleep. Nature, 185-90.
268066061:1000Alexander, G.M., et al. 2016. Social and novel contexts modify hippocampal CA2 representations of space.. Nature Communications, 10300.
266440851:100Althaus, A.L., et al. 2016. Axonal plasticity of age-defined dentate granule cells in a rat model of mesial temporal lobe epilepsy. Neurobiology of Disease, 187-96.
PLA: Mouse
PMID Dilution Publication
369714281:500Samadi, M., et al. 2023. Mechanisms of mGluR-Dependent Plasticity in Hippocampal Area CA2. Hippocampus, .
Western Blot: Human
PMID Dilution Publication
238177831:1000-5000Evans, P.R., et al. 2013. Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.. Journal of Comparative Neurology, 186-203.
232507581:50Vellano, C.P., et al. 2013. Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.. The Journal of Biological Chemistry, 3620-31.
Western Blot: Mouse
PMID Dilution Publication
370759481:500Harbin, N.H., et al. 2023. RGS14 Limits Seizure-Induced Mitochondrial Oxidative Stress and Pathology in Hippocampus. Neurobiology of Disease, 106128.
313191671:500Alexander, G. M., et al. 2019. Modulation of CA2 Neuronal Activity Increases Behavioral Responses to Fear Conditioning in Female Mice. Neurobiology of Learning and Memory, 107044.
289576651:500Basu, R., et al. 2017. Heterophilic type II cadherins are required for high-magnitude synaptic potentiation in the hippocampus. . Neuron, 160-176.
238177831:1000-5000Evans, P.R., et al. 2013. Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.. Journal of Comparative Neurology, 186-203.

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