Our Anti-QKI-7 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N183/15. It detects human and mouse QKI-7, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
QKI7 is a member of the Signal Transduction and Activation of RNA proteins (STAR proteins) family. QKI5, QKI6, QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. QKI7 is a RNA-binding protein. QKI6 has roles in the regulation of splicing, export and stability of mRNA. It is involved in myelinization. It is a cytoplasmic isoform. Diseases associated with this gene include Angiocentric Glioma, 6Q Terminal Deletion Syndrome and Schizophrenia.
Purified by Protein A chromatography
Qki Qk QKI HKQ Qk1 Qka1
Synthetic peptide amino acids 303-317 (LEWIEMPVMPDISAH, C-terminal tail) of human QKI-7 (accession number Q96PU8-5)
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL550 Ex: 550 nm, Em: 575 nm
Does not cross-react with QKI-5, QKI-6 or QKI-7b
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.