Anti-QKI-7 Antibody (N183/15)

from NeuroMab Datasheet
15 Citations

Available Conjugates

490
550
594
650

Primary Antibody
Human, Mouse
N183/15
ICC, IHC, WB
Mouse
Purified by Protein A chromatography
Qki Qk QKI HKQ Qk1 Qka1
36-38 kDa

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Adult rat hippocampus immunohistochemistry.
Adult rat brain membrane immunoblot.
Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged QKI-5, QKI-6, QKI-7 and QKI-7b and untagged Kv2.1 plasmids and probed with N183/15 (left) and mouse anti-Flag (right.
Western blot of protein extracted from UD hESCs, DE cells, and CM cells probed with antibodies for QKI5 (magenta, top panel) and panQKI (green), QKI6 (magenta, middle panel) and panQKI (green), or QKI7 (magenta, bottom panel; ND denotes not detectable) and panQKI (green). Image from publication CC-BY-4.0. PMID: 35544276
Double immunofluorescence revealing pruned Lewy Neurites (pSyn, Red) and the cytoplasms of mature mouse OLs (QKI-7, cat. 75-200, 1:500; green) at the level of the anterior commissure of a mouse 6 months after the intrastriatal injection of α-Syn PFFs. Horizontal brain section. Nuclei are counterstained with DRAQ7 (white). Image from publication CC-BY-4.0. PMID:36830639
Adult rat hippocampus immunohistochemistry.
Adult rat hippocampus immunohistochemistry.
Adult rat brain membrane immunoblot.
Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged QKI-5, QKI-6, QKI-7 and QKI-7b and untagged Kv2.1 plasmids and probed with N183/15 (left) and mouse anti-Flag (right.
Western blot of protein extracted from UD hESCs, DE cells, and CM cells probed with antibodies for QKI5 (magenta, top panel) and panQKI (green), QKI6 (magenta, middle panel) and panQKI (green), or QKI7 (magenta, bottom panel; ND denotes not detectable) and panQKI (green). Image from publication CC-BY-4.0. PMID: 35544276
Double immunofluorescence revealing pruned Lewy Neurites (pSyn, Red) and the cytoplasms of mature mouse OLs (QKI-7, cat. 75-200, 1:500; green) at the level of the anterior commissure of a mouse 6 months after the intrastriatal injection of α-Syn PFFs. Horizontal brain section. Nuclei are counterstained with DRAQ7 (white). Image from publication CC-BY-4.0. PMID:36830639

Anti-QKI-7 Antibody
SKU: 75-200

Volume: 100 µL
1-2 business days
Price:
$308

Bulk Order Anti-QKI-7 Antibody

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
327328891:100Yang, C., et al. 2020. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nature Communications, 3812.
Immunohistochemistry: Human
PMID Dilution Publication
2702940510ug/mlde Bruin, R.G., et al. 2014. Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression.. Nature Communications, 10846.
23963726not listedvan der Veer, E.P., et al. 2013. Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype.. Circulation Research, 1065-1075.
Immunohistochemistry: Mouse
PMID Dilution Publication
368306391:500De Nuccio, F., et al. 2023. Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?. Biomolecules, 269.
274543261:100Bin, J.M., et al. 2016. The oligodendrocyte-specific antibody ''CC1'' binds Quaking 7.. Journal of Neurochemistry, 181-186.
27196066not listedSuiko, T., et al. 2016. Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina. PLoS One, e0156033.
Western Blot: Human
PMID Dilution Publication
37379838not listedZhao, Z, et al. 2023. QKI Shuttles Internal m7G-modified Transcripts into Stress Granules and Modulates mRNA Metabolism. Cell, .
35544276not listedFagg, W.S., et al. 2022. Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate. Nucleic acids research, 5313-5334.
244499171:1000Chan, C.B., et al. 2014. PIKE is essential for oligodendroglia development and CNS myelination.. PNAS: USA, 1993-1998.
Western Blot: Mouse
PMID Dilution Publication
327328891:1000Yang, C., et al. 2020. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nature Communications, 3812.
274543261:1000Bin, J.M., et al. 2016. The oligodendrocyte-specific antibody ''CC1'' binds Quaking 7.. Journal of Neurochemistry, 181-186.
27196066not listedSuiko, T., et al. 2016. Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina. PLoS One, e0156033.

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