Anti-Prox1 Antibody (5G10)

Name: Anti-Prox1 Antibody
Brand: PhosphoSolutions
SKU: 1685-PROX1
Price: 456.0 USD
Availability: InStock

Our Anti-Prox1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, rat Prox1 and is Protein G purified. It is great for use in IHC.

Immunostaining of rat dentate gyrus showing specific immunolabeling of the Prox1 protein(DAB, 1:1000). Photo courtesy of Justin Kievits and Teresa Milner, Weill Cornell Medical College.

Click on image to zoom

Species Reactivity

Chicken, Human, Mouse, Rat

Applications

ELISA, IHC

Host Species

mouse

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Data Sheet

Trial Size

SKU: 1685-PROX1

Volume: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Prox1

Scientific Background

Prox1 (Prospero-related homeobox 1) is a divergent homeogene that regulates cell proliferation, fate determination and differentiation during vertebrate embryonic development. The protein is expressed in the developing lens and is also detected in embryonic brain, lung, liver and kidney; while in adult it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas (Chen et al., 2006). Prox1 is thought to play a fundamental role in early development of the CNS and may regulate gene expression and development of postmitotic undifferentiated young neurons (Misra et al., 2008)

Format

Protein G Purified

Clonality

Monoclonal

Clone

5G10

Isotype

IgG1

Applications

ELISA, IHC

Host Species

mouse

Gene Name

PROX1

Immunogen

Recombinant human Prox1 protein.

Immunogen Species

Human

Species Reactivity

Chicken, Human, Mouse, Rat

Antibody Registry ID

AB_2492217

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Protein G purified culture supernatant.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

IHC: 1:1000

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of Prox1.

Quality Control

Immunohistochemistry performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

Homeobox prospero like protein; Homeobox prospero like protein PROX1; Homeobox prospero-like protein PROX1; Prospero homeobox 1; Prospero homeobox protein 1; Prospero related homeobox 1; prospero-related homeobox gene 1; PROX 1; PROX-1; PROX1; PROX1_HUMAN; zgc:111888

UniProt ID

Q92786
UniProt Summary: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. {ECO:0000269|PubMed:23723244, ECO:0000303|PubMed:22733308}.

NCBI Gene ID

5629

Shipping

Blue Ice

Prox1 IHC Protocol: Download

Western Blot Protocol: Download

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Anti-Prox1 Antibody (5G10)

SKU: 1685-PROX1

Product Details

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