Anti-Parathyroid hormone 2 receptor (PTH2 receptor) Antibody

Name: Anti-Parathyroid hormone 2 receptor (PTH2 receptor) Antibody
Brand: Biosensis
SKU: R-120-100
Price: 327.0 USD
Availability: InStock

Our Anti-Parathyroid hormone 2 receptor (PTH2 receptor) rabbit polyclonal primary antibody detects rat Parathyroid hormone 2 receptor (PTH2 receptor), and is whole serum. It is validated for use in WB.

Western blot analysis of rat brain using Rabbit antibody to PTH2 receptor (481-501): whole serum (catalogue no. R-120-100) isolated a major band of 63 kDa corresponding to the theoretical molecular weight of Parathyroid hormone receptor.

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Species Reactivity

Rat

Applications

Host Species

Rabbit

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Data Sheet

SKU: R-120-100

Volume/Size: 100 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Parathyroid hormone 2 receptor (PTH2 receptor)

Scientific Background

FUNCTION: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by g proteins which activate adenylyl cyclase. PTHR2 may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTHR2 presence in neurons indicates that it may function as a neurotransmitter receptor. SUBUNIT: Binds to TIPF39/TIP39. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. TISSUE SPECIFICITY: Abundantly expressed in brain, arterial and cardiac endothelium. Found as well in sperm, in the head of the epididymis. Lower expression is found in vascular smooth muscle, exocrine pancreas, testis and placenta. SIMILARITY: Belongs to the G-protein coupled receptor 2 family.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

Host Species

Rabbit

Molecular Weight

63 kDa

Immunogen

A synthetic peptide (RQIDSHVTLPGYVWSSSEQDC) of rat Parathyroid hormone receptor protein (aa: 481-501) conjugated to KLH has been used as the immunogen.

Immunogen Species

Rat

Species Reactivity

Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

WB: 1:500-1:1000

Conjugate

Unconjugated

Specificity

Specificity has been shown by Western blot. A band of 63 kDa corresponding to the theoretical molecular weight of Parathyroid hormone receptor is easily detectable by WB. Absorption of the antiserum with the immunising peptide abolished the binding of the antibody to the target hence detectability of the band. This antibody is known to react with rat Parathyroid hormone receptor.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Parathyroid hormone receptor; PTH2 receptor; Pthr2;

UniProt ID

P70555

Shipping

25°C (ambient)

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Anti-Parathyroid hormone 2 receptor (PTH2 receptor) Antibody

SKU: R-120-100

Product Details

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