Anti-Pan-Kvbeta Potassium Channel Antibody (K25/73)

Name: Anti-Pan-Kvbeta Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-392
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

K25/73

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kcnab1 Kvb1 Kcnab3 Ckbeta3 Kcnab2 Ckbeta2 Kcnb3

Molecular Weight

40 kDa

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Adult rat brain membrane immunoblot

Volume: 100 µL

Variant

Price:

$308

Quantity:

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Product Details

Target

Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1) Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3) (RCK beta3) Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2)

Target Description

The ß subunits of voltage-gated potassium channels are members of the potassium channel, voltage-gated, shaker-related subfamily. Kvßs are cytoplasmic subunits that modulate the characteristics of the membrane spanning, channel-forming alpha-subunits. Beta subunits can promote the closure of channels or enhance channel activity depending on other channel proteins. There are three ß subunits (Kvß1, Kvß2, Kvß3) which are coded by three different genes. Additionally, there is alternative splicing of these three genes, further diversifying the functions and tissue expression of the family.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K25/73

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnab1 Kvb1 Kcnab3 Ckbeta3 Kcnab2 Ckbeta2 Kcnb3

Molecular Weight

40 kDa

Antigen

Synthetic peptide amino acids 350-367 (EIDSILGNKPYSKKDYRS, C-terminus) of human Kvbeta2 (also known as Voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, Neuroimmune protein F5, KCNAB2, KCNA2B, KCNK2, Ckbeta2, I2rf5 and Kcnb3, accession number Q13303); Mouse: 100% identity (18/18 amino acids identical); Rat: 100% identity (18/18 amino acids identical) 75% identity with Kvbeta1 and Kvbeta3

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2491089

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Reacts with Kvbeta1

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

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Anti-Pan-Kvbeta Potassium Channel Antibody (K25/73)

Anti-Pan-Kvbeta Potassium Channel Antibody
SKU: 75-392

Bulk Order Anti-Pan-Kvbeta Potassium Channel Antibody

Product Details

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Anti-Pan-Kvbeta Potassium Channel Antibody (K25/73)

Anti-Pan-Kvbeta Potassium Channel Antibody SKU: 75-392

Bulk Order Anti-Pan-Kvbeta Potassium Channel Antibody

Product Details

Anti-Pan-Kvbeta Potassium Channel Antibody
SKU: 75-392