Anti-Pan-Kvbeta K+ Channel Antibody (K40/17)

Name: Anti-Pan-Kvbeta K+ Channel Antibody
Brand: NeuroMab
SKU: 75-106
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

K40/17

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kcnab1 Kvb1 Kcnab3 Ckbeta3 Kcnab2 Ckbeta2 Kcnb3

Molecular Weight

30-45 kDa

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$Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with K40/17 (left) or N52A/42 (right) TC supe.$

Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with K40/17 (left) or N52A/42 (right) TC supe.

Volume: 100 µL

Variant

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Product Details

Target

Pan-Kvbeta K+ channel

Target Description

The ß subunits of voltage-gated potassium channels are members of the potassium channel, voltage-gated, shaker-related subfamily. Kvßs are cytoplasmic subunits that modulate the characteristics of the membrane spanning, channel-forming alpha-subunits. Beta subunits can promote the closure of channels or enhance channel activity depending on other channel proteins. There are three ß subunits (Kvß1, Kvß2, Kvß3) which are coded by three different genes. Additionally, there is alternative splicing of these three genes, further diversifying the functions and tissue expression of the family.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K40/17

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

Kcnab1 Kvb1 Kcnab3 Ckbeta3 Kcnab2 Ckbeta2 Kcnb3

Molecular Weight

30-45 kDa

Antigen

Fusion protein amino acids 1-401 (full-length) of rat Kv1 (also known as voltage-gated potassium channel subunit beta-1, accession number P63144); Mouse: 100% identity (401/401 amino acids identical); Human: 100% identity (401/401 amino acids identical) Greater than 80% identity with Kv2 Greater than 60% identity with Kv3

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2131361

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1) Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3) (RCK beta3) Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2)

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Anti-Pan-Kvbeta K+ Channel Antibody (K40/17)

Anti-Pan-Kvbeta K+ Channel Antibody
SKU: 75-106

Bulk Order Anti-Pan-Kvbeta K+ Channel Antibody

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Anti-Pan-Kvbeta K+ Channel Antibody (K40/17)

Anti-Pan-Kvbeta K+ Channel Antibody SKU: 75-106

Bulk Order Anti-Pan-Kvbeta K+ Channel Antibody

Product Details

Anti-Pan-Kvbeta K+ Channel Antibody
SKU: 75-106