Anti-Olig2 Antibody
SKU: OLIG2-0100
Product Details
Olig2
OLIG2 (also known as BHLHB1, BHLHE19, PRKCBP2, RACK17) is a basic helix-loop-helix (bHLH) transcription factor essential for oligodendrocyte and motoneuron development in the spinal cord (Ono et al., 2008). OLIG2 is also known to play a key role in mediating the brains response to cortical injury through post-injury gliosis (Chen Y et al., 2008) and is also highly expressed in malignant glioma where it has been implicated in glioma progression.
Affinity Purified IgY
0.2 mg/mL
Polyclonal
IgY
ICC, IHC, WB
Chicken
OLIG2
35 kDa
N-terminal half of human OLIG2 was used to immunize chickens to avoid cross-reactivity with OLIG3.
Human, Mouse, Rat
AB_2924438
Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Liquid
Eggs from hens hyperimmunized with target were used to prepare an IgY fraction which was then subjected to antigen-specific affinity purification.
Phosphate-buffered saline (10 mM) isotonic (0.9%, w/v) saline (“PBS," pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
WB: 1:1000
IHC: 1:1000
ICC: 1:1000
IHC: 1:1000
ICC: 1:1000
No cross reactivity reported.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used in Western blot on lysate from cells expressing Olig2.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
1 year from date of receipt
Ice packs
BHLHB1, BHLHE19, PRKCBP2, RACK17
UniProt (Human): Q13516
UniProt (Immunogen Species): Q13516
UniProt (Immunogen Species): Q13516
Product Specific References for Applications and Species
Immunocytochemistry: Mouse | ||
PMID | Dilution | Publication |
38664376 | not listed | Liu, X, et al. 2024. Numb positively regulates Hedgehog signaling at the ciliary pocket. Nature Communications, 3365. |
TUNEL: Mouse | ||
PMID | Dilution | Publication |
38317026 | not listed | Logsdon, AF, et al. 2024. Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration. Journal of neurochemistry, . |