Anti-Nociceptin Antibody

Name: Anti-Nociceptin Antibody
Brand: Biosensis
SKU: R-105-100
Price: 327.0 USD
Availability: InStock

Our Anti-Nociceptin rabbit polyclonal primary antibody detects guinea pig, and rat Nociceptin, and is whole serum. It is validated for use in ELISA, IHC-Frozen.

Species Reactivity

Guinea Pig, Pig, Rat

Applications

ELISA, IHC

Host Species

Rabbit

Go to Full Product Details

Data Sheet

SKU: R-105-100

Volume/Size: 100 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Nociceptin

Scientific Background

FUNCTION: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. PTM: Specific enzymatic cleavages at paired basic residues probably yield other active peptides besides nociceptin. PTM: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. SIMILARITY: Belongs to the opioid neuropeptide precursor family.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

ELISA, IHC

Host Species

Rabbit

Immunogen

A synthetic peptide (C-TG ARKSARKLAN Q) as part of rat Nociceptin peptide (aa: 139-151) conjugated to diphtheria toxoid

Immunogen Species

Rat

Species Reactivity

Guinea Pig, Pig, Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

IHC: 1:1000-1:3000
ELISA: 1:1000-1:3000

Application Details

This antibody may also be used for staining of nerve fibres in guinea pig myenteric plexus.

Conjugate

Unconjugated

Specificity

Specificity has been tested by the use of different peptides including enkephalin, dynorphin and endorphin for absorption in immunihistochemistry. This antibody is known to cross react with guinea pig and rat.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

There are no synonyms for this peptide; however the precursor protein contains: Neuropeptide 1; Nociceptin (Orphanin FQ; PPNOC; ORL1 receptor agonist); Neuropeptide 2

UniProt ID

Q62923

Shipping

25°C (ambient)

Recover password

Create my account

Anti-Nociceptin Antibody

SKU: R-105-100

Product Details

Bulk Order Anti-Nociceptin Antibody

Related Products

Recently Viewed