Anti-Neuropeptide RFRP-3 Antibody

Name: Anti-Neuropeptide RFRP-3 Antibody
Brand: Biosensis
SKU: GP-1080-50
Price: 337.0 USD
Availability: InStock

Our Anti-Neuropeptide RFRP-3 guinea pig polyclonal primary antibody detects human, rat, and sheep Neuropeptide RFRP-3, and is whole serum. It is validated for use in IHC-Frozen.

Immunoreactivity of cells and terminals in sheep hypothalamus section using anti-RFRP-3 antibody (1:2000).

Staining of RFRP-3 peptide is not affected by preadsorption with Kisspeptin.

Staining of RFRP-3 peptide is not affected by preadsorption with Prolactin-releasing peptide (PrRP).

Staining of RFRP-3 peptide is not affected by preadsorption with NFF peptide.

Immunohistochemical detection of RFRP-3 with the guinea pig polyclonal antiserum (gp-1080-50; 1: 40,000), followed by detection with the biotinylated secondary antibody-ABC method and nickel-diaminobenzidine chromogen, produces specific labeling of RFRP-3/GnIH neurons and their processes in the dorsomedial nucleus of the rat hypothalamus. Photo courtesy of Dr. Erik Hrabovszky, Hungarian Academy of Sciences, Budapest, Hungary.

Immunoreactivity of cells and terminals in sheep hypothalamus section using anti-RFRP-3 antibody (1:2000).

Click on image to zoom

Species Reactivity

Human, Rat, Sheep

Applications

IHC

Host Species

Guinea Pig

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Data Sheet

SKU: GP-1080-50

Volume/Size: 50 µL

Variant

Price:

$337.00

Quantity:

Product Details

Target

Neuropeptide RFRP-3

Scientific Background

Neuropeptide VF is the precursor of neuropeptides NPSF (RFRP-1), RFRP-2 and RFRP-3 (NPVF). RFRP-3 is reported to inhibit forskolin-induced production of cAMP. RFRP-3 has also been shown to block morphine-induced analgesia.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

IHC

Host Species

Guinea Pig

Immunogen

A synthetic peptide (VPNLPQRF) corresponding to the amino acids 124-131 from human Neuropeptide VF. Neuropeptide VF is the precursor of the neuropeptides NPSF (RFRP-1), RFRP-2 and RFRP-3. The synthetic peptide was conjugated to a carrier protein KLH to enhance the immunological response.

Immunogen Species

Human

Species Reactivity

Human, Rat, Sheep

Storage

Spin vial briefly before opening. Reconstitute in 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C or lower. After reconstitution, divide into aliquots and store at -20°C, or lower, for optimal long term stability. It is recommended that a reconstituted aliquot is stored at 2-8°C for no longer than 2 weeks. Allocation of an appropriate anti-bacterial agent can increase shelf life by several weeks. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.

Physical State

Lyophilized

Production Notes

Neat serum

Dilution Ranges

IHC: 1:2000

Application Details

IHC performed in sheep brain (hypothalamus) demonstrates intense staining of cells and terminals.

Conjugate

Unconjugated

Specificity

Specificity was demonstrated by immunohistochemistry. This antibody is known to react with rat and sheep.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (lyophilized, unopened vial).

Synonyms

Neuropeptide NPVF; RFRP; Neuropeptide VF; C7orf9; FMRFamide-related peptides;

UniProt ID

Q9HCQ7

Shipping

25°C (ambient)

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Anti-Neuropeptide RFRP-3 Antibody

SKU: GP-1080-50

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