Adult mouse brain membrane (MBM) and transfected cell immunoblot: extracts of MBM and COS cells transiently transfected with Neuroligin-1 and Neuroligin-4* plasmids and probed with N98/47. Data courtesy of Marc Bolliger and Tom Sudhof, UTSW (now at Stanford).
Bulk Order Anti-Neuroligin-4* Antibody
Neuroligin4 is encoded by the gene NLGN4. Neuroligin4 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including retina and brain, where it is located at the postysynaptic membrane and is involved in regulation of synapses, synapse formation and synaptic transmission. Diseases associated with this gene include forms of Autism and Asperger Syndrome.
Purified by Protein A chromatography
Nlgn4l Nl4* Nlgn4 Nlgn4x
Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin-4* (accession number ABS19580) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.67
Does not cross-react with other Neuroligins
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.