Transfected cell immunofluorescence: COS cells expressing Flag-tagged human Neureguline-HBD. Red = rabbit anti-Flag, Green = N120A/9.
Anti-Neuregulin-HBD (Heparin Binding Domain, Type I/II) Antibody
Neuregulin-HBD (Heparin binding domain, Type I/II)
Neuregulin 1 is encoded by the gene NRG1. NRG1 is a member of the neuregulin family. NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. NRG1 is expressed in the nervous system, intestine, muscle, and heart. Diseases associated with NRG1 include Schizphrenia 6 and Lung Cancer.
NRG1 GGF HGL HRGA NDF SMDF
Fusion protein amino acids 14-117 (extracellular N-terminus) of human Neuregulin-1(also known as NRG1, Neu differentiation factor, NDF, Heregulin, HRG, HGL, Breast cancer cell differentiation factor p45, Acetylcholine receptor-inducing activity, ARIA, Glial growth factor, GGF, Sensory and motor-neuron-derived factor or SMDF, accession number Q02297); Rat: 91% identity (95/104 amino acids identical); Mouse: 90%identity (91/104 amino acids identical); Less than 40% identity with NRG2
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]