Anti-Navbeta1 Na+ Channel Antibody (N405/74)

Name: Anti-Navbeta1 Na+ Channel Antibody
Brand: NeuroMab
SKU: 75-425
Price: 329.0 USD
Availability: InStock

Our Anti-Navbeta1 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N405/74. It detects mouse and rat Navbeta1 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-425

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Navbeta1 Na+ channel

Scientific Background

Sodium channel subunit beta-1or Navbeta1 Na+ channel is encoded by SCN1B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. SCN1B has two splice variants. Navß1 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel inactivation. It is found expressed in brain, spinal cord, heart and skeletal muscle. Diseases associated with SCN1B include several types of epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N405/74

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Scn1b

Molecular Weight

24 kDa

Immunogen

Fusion protein amino acids 14-160 (extracellular N-terminus) of rat Navbeta1 (accession number Q00954) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2637012

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Navbeta2, Navbeta3 or Navbeta4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Sodium channel subunit beta-1

UniProt ID

Q00954

Shipping

Shipped on ice packs

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Anti-Navbeta1 Na+ Channel Antibody (N405/74)

SKU: 75-425

Product Details

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