Anti-MANF Antibody

Name: Anti-MANF Antibody
Brand: Biosensis
SKU: M-1673-100
Price: 457.0 USD
Availability: InStock

Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) mouse monoclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is IgG. It is validated for use in WB.

Western Blot testing of anti-MANF monoclonal antibody. Line 1. PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2. Purified recombinant MANF (500 ng per line) expressed using CHOEBNALT85 cell line.

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Species Reactivity

Human

Applications

Host Species

Mouse

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Data Sheet

SKU: M-1673-100

Volume/Size: 100 µg

Variant

Price:

$457.00

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Product Details

Target

Mesencephalic astrocyte-derived neurotrophic factor (MANF)

Scientific Background

MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson's disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

Format

IgG

Clonality

Monoclonal

Isotype

IgG1

Applications

Host Species

Mouse

Immunogen

Recombinant human MANF protein produced using CHO-based cell line. Immunogen is purified from cell culture supernatant.

Immunogen Species

Human

Species Reactivity

Human

Storage

Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.

Physical State

Liquid

Production Notes

Purified with Protein G affinity chromatography

Buffer

PBS pH 7.4, with 0.1% sodium azide

Dilution Ranges

WB: 0.5-2 µg/mL
IHC: 1-10 µg/mL
ICC: 1-10 µg/mL
ELISA: 0.1-0.2 µg/mL (indirect)

Conjugate

Unconjugated

Specificity

MANF (Mesencephalic astrocyte-derived neurotrophic factor).

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

ARMET, ARP

UniProt ID

P55145

Shipping

25°C (ambient)

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Anti-MANF Antibody

SKU: M-1673-100

Product Details

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