Anti-LRRTM2 Antibody (N209C/35)

Name: Anti-LRRTM2 Antibody
Brand: NeuroMab
SKU: 75-364
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

1 Citation

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N209C/35

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

LRRTM2 KIAA0416 LRRN2

Molecular Weight

80 kDa (and larger due to glycosylation)

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Immunoblot against crude brain membrane preparations from adult rat (RBM) or extracts of COS cells transiently transfected with Myc- tagged LRRTM1, LRRTM2 or untagged Kv2.1 plasmid probed with N209C/35 (left), K89/34 (middle) or N52A/42 (right) TC supe.

Volume: 100 µL

Variant

Price:

$308

Quantity:

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Product Details

Target

Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)

Target Description

Leucine Rich Repeat Transmembrane Neuronal 2 is encoded by the gene LRRTM2. LRRTM2 is a member of the LRRTM family. LRRTM2 is involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. LRRTM2 is expressed in neuronal tissues. Diseases associated with LRRTM2 include Histrionic Personality Disorder.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N209C/35

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

LRRTM2 KIAA0416 LRRN2

Molecular Weight

80 kDa (and larger due to glycosylation)

Antigen

Synthetic peptide amino acids 475-489 (MSNMSDQGPYNEYEP, cytoplasmic C-terminus) of human LRRTM2 (also known as Leucine-rich repeat transmembrane neuronal protein 2, Leucinerich repeat neuronal 2 protein, LRRN2 and KIAA0416, accession number O43300); Mouse: 100% identity (15/15 amino acids identical); Rat: 93% identity (14/15 amino acids identical); Less than 50% identity with LRRTM1, LRRTM3 and LRRTM4

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2315886

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with LRRTM1

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)

UniProt Details

UniProt (Human): O43300
UniProt (Immunogen Species): O43300

Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D. (2015), 'Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation..' Cell Rep.. 10.1016/j.celrep.2015.04.043.

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Anti-LRRTM2 Antibody (N209C/35)

Anti-LRRTM2 Antibody
SKU: 75-364

Bulk Order Anti-LRRTM2 Antibody

Product Details

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Anti-LRRTM2 Antibody (N209C/35)

Anti-LRRTM2 Antibody SKU: 75-364

Bulk Order Anti-LRRTM2 Antibody

Product Details

Anti-LRRTM2 Antibody
SKU: 75-364