Low-density lipoprotein receptor-related protein 4 or LRP4 is encoded by the gene LRP4. And is a member of the low-density lipoprotein receptor-related protein family. Proteins in this family function in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment. LRP4 may be involved in the negative regulation of the canonical Wnt signaling pathway. LRP4 is expressed in bone and several regions of the brain. Mutations in this gene are associated with Cenani-Lenz syndrome.
Purified
1 mg/mL
Monoclonal
N207/27
IgG2a
ICC, WB
Mouse
Lrp4 Kiaa0816
215 kDa
Fusion protein amino acids 26-350 (extracellular N-terminus) of mouse LRP4(also known as Lowdensity lipoprotein receptor-related protein 4, LDLR dan, Multiple epidermal growth factor-like domains 7, MEGF7 and KIAA0816, accession number Q8VI56); Rat: 98% identity (321/325 amino acids identical); Human: 97% identity (317/325 amino acids identical)
Less than 50% identity with LRP1
Mouse, Rat
AB_2139030
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Unconjugated
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)
