Anti-Lgi1 Antibody FL490 Conjugate (N283/7)

Name: Anti-Lgi1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-307-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Lgi1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N283/7. It is KO validated, detects human, mouse, and rat Lgi1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-307-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Lgi1

Target Description

Leucine Rich Glioma Inactivated 1 is encoded by the gene LGI1. LGI1 is a member of the secreted leucine-rich repeat (LRR) superfamily. LGI1 may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. LGI1 is expressed in the brain. Diseases associated with LGI1 include Epilepsy, Familial Temporal Lobe, 1 and Autosomal Dominant Epilepsy with Auditory Features.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N283/7

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Lgi1

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse Lgi1 (accession number Q9JIA1) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940072

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Lgi2, Lgi3 or Lgi4 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Leucine-rich glioma-inactivated protein 1

UniProt Details

UniProt (Human): O95970
UniProt (Immunogen Species): Q9JIA1

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Anti-Lgi1 Antibody FL490 Conjugate (N283/7)

SKU: 75-307-FL490

Product Details

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