Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM (left lane) and COS-1 cells transiently transfected with KCNQ4 (middle lane) or Kv2.1 (right lane) plasmids and probed with pure N43/6 (left panel) or K89/41 TC supe (right panel).
Anti-Kv7.4/KCNQ4 K+ Channel Antibody
Kv7.4/KCNQ4 K+ channel
Potassium voltage-gated channel subfamily KQT member 4, Voltage-Gated Potassium Channel Subunit Kv7.4 or KCNQ4 is encoded by the gene KCNQ4. KCNQ4 is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. It is found in the outer hair cell of cochlea, brain, heart, and skeletal muscle. Diseases associated with KCNQ4 include types of deafness.
ICC, IP, WB
Fusion protein amino acids 2-77 of human KCNQ4(Kv7.4, KvLQT4, accession number P56696); Mouse: 94% identity (71/75 amino acids identical); Rat: 94% identity (71/75 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.