Anti-Kv7.1/KCNQ1 K+ Channel Antibody (N37A/10)

Name: Anti-Kv7.1/KCNQ1 K+ Channel Antibody
Brand: NeuroMab
SKU: 75-081
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

KCNQ1 KCNA8 KCNA9 KVLQT1

Molecular Weight

75 kDa

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Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM (left lane) and COS-1 cells transiently transfected with flag-tagged KCNQ1 (middle lane) or Kv2.1 (right lane) plasmids and probed with pure N37A/10 (left panel), rabbit anti-flag (middle panel) or K89/41 TC supe (right panel).

Transfected cell immunofluorescence: COS-1 cells expressing KCNQ1. Red = N37A/10, Blue = Hoechst nuclear stain.

Product Details

Target

Kv7.1/KCNQ1 K+ channel

Target Description

Potassium voltage-gated channel subfamily Q member 1 is encoded by the gene KCNQ1. KCNQ1 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.1/KCNQ1 sub-subfamily. KCNQ1 is a voltage-gated potassium channel that is required for the repolarization phase of the cardiac action potential. KCNQ1 can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. KCNQ1 is expressed in the heart, pancreas, kidney, prostate, small intestine, and peripheral blood leukocytes. Diseases associated with KCNQ1 include Long QT Syndrome1, Jervell and Lange-Nielsen Syndrome, atrial fibrillation familial 3, short QT syndrome 2, and atrial fibrillation.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N37A/10

Isotype

IgG1

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

KCNQ1 KCNA8 KCNA9 KVLQT1

Molecular Weight

75 kDa

Antigen

Fusion protein amino acids 2-101 of human KCNQ1(Kv7.1, KvLQT1, accession number P51787); Rat: 72% identity (71/98 amino acids identical); Mouse: 63% identity (62/98 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2131682

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium voltage-gated channel subfamily KQT member 1 (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1) (Voltage-gated potassium channel subunit Kv7.1)

UniProt Details

UniProt (Human): P51787
UniProt (Immunogen Species): P51787

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Anti-Kv7.1/KCNQ1 K+ Channel Antibody (N37A/10)

Anti-Kv7.1/KCNQ1 K+ Channel Antibody
SKU: 75-081

Product Details

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Anti-Kv7.1/KCNQ1 K+ Channel Antibody (N37A/10)

Anti-Kv7.1/KCNQ1 K+ Channel Antibody SKU: 75-081

Product Details

Anti-Kv7.1/KCNQ1 K+ Channel Antibody
SKU: 75-081