Anti-Kirrel3 Short And Long Antibody (N321C/49)

Name: Anti-Kirrel3 Short And Long Antibody
Brand: NeuroMab
SKU: 75-333
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N321C/49

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kirrel3 Kirrel3_predicted

Molecular Weight

85-105 kDa (multiple isoforms)

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Tissue and transfected cell immunoblot: extracts of rat brain membrane (RBM) and COS cells transiently transfected with Flag-tagged Kirrel3-short, Kirrel3-long, untagged Kirrel2, Kirrel1 or Kv2.1 plasmid and probed with N321C/49 (left) and N52A/42 (right) TC supe.

Volume: 100 µL

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Product Details

Target

Membrane protein KIRRE

Target Description

Kirre Like Nephrin Family Adhesion Molecule 3 is encoded by the gene KIRREL3. KIRREL3 is a member of the immunoglobulin superfamily, nephrin-like protein family. KIRREL3 is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. KIRREL3 is expressed in brain, bone marrow, and stromal cells. Diseases associated with KIRREL3 include Autosomal Dominant Non-Syndromic Intellectual Disability and Autosomal Dominant Non-Syndromic Intellectual Disability 4.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N321C/49

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

Kirrel3 Kirrel3_predicted

Molecular Weight

85-105 kDa (multiple isoforms)

Antigen

Fusion protein amino acids 46-524 (extracellular N-terminus) of rat Kirrel3 (also known as Kin of irregular chiasm-like protein 3, Kin of IRRE-like protein 3, Nephrin-like protein 2, NEPH2 and Kiaa1867, accession number Q09GS6) Mouse: 97% identity (479/491 amino acids identical); Human: 95% identity (470/491 amino acids identical); 100% identity between short and long isoforms; ~50% identity with Kirrel1 and Kirrel2

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315857

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Reacts with Kirrel3 short and long isoforms Does not cross-react with Kirrel1 and Kirrel2

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Membrane protein KIRRE

UniProt Details

UniProt (Human): Q8IZU9
UniProt (Immunogen Species): Q09GS6

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Anti-Kirrel3 Short And Long Antibody (N321C/49)

Anti-Kirrel3 Short And Long Antibody
SKU: 75-333

Bulk Order Anti-Kirrel3 Short And Long Antibody

Product Details

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Anti-Kirrel3 Short And Long Antibody (N321C/49)

Anti-Kirrel3 Short And Long Antibody SKU: 75-333

Bulk Order Anti-Kirrel3 Short And Long Antibody

Product Details

Anti-Kirrel3 Short And Long Antibody
SKU: 75-333