Anti-Kir6.1 Potassium Channel Antibody FL594 Conjugate (N366/60)
Our Anti-Kir6.1 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N366/60. It detects mouse and rat Kir6.1 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: 75-394-FL594
Product Details
Kir6.1 potassium channel
ATP-sensitive inward rectifier potassium channel 8 or Kir6.1 is encoded by the gene Kcnj8. Kir6.1 is an integral membrane protein which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. In this manner, Kir6.1 plays a role in modifying Ca2+ release from intracellular stores. Kir6.1 is expressed in many tissues including in pancreatic islets, brain, skeletal muscle and heart and found distributed in mitochondria and endoplasmic reticulum. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS) and Cantu Syndrome.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N366/60
IgG2a
ICC, IHC
Mouse
Kcnj8
45 kDa
Fusion protein amino acids 306-424 (cytoplasmic C-terminus) of rat Kir6.1 (accession number Q63664) produced recombinantly in E. Coli
Mouse, Rat
AB_2940298
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
Does not cross-react with Kir6.2
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1)
UniProt (Human): Q15842
UniProt (Immunogen Species): Q63664
UniProt (Immunogen Species): Q63664