Anti-KChIP3 K+ Channel Antibody FL490 Conjugate (K66/38)

Name: Anti-KChIP3 K+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-005-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-KChIP3 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K66/38. It is KO validated, detects human, mouse, and rat KChIP3 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-005-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

KChIP3 K+ channel

Target Description

Kchip3 potassium channel, also known as Kv channel-interacting protein 3, Kcnip3, DREantagonist modulator and Dream is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip3 is an integral subunit component of native Kv4 channel complexes that may regulate A-type currents and function as a calcium regulated transcriptional repressor. Kchip3 is detected in brain, specifically in the cortex, thalamus, dentate gyrus and cerebellum and can be found throughout the cell. It is also found in other tissues at low levels. Diseases associated with KCNIP3 include alzheimer disease.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

K66/38

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnip3 Csen Dream Kchip3

Molecular Weight

34 kDa

Antigen

Fusion protein amino acids 1-256 (full length) of rat Calsenillin/DREAM/KChIP3 (accession number Q9JM47) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939080

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against rat KChIPs 1,2, 4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)

UniProt Details

UniProt (Human): Q9Y2W7
UniProt (Immunogen Species): Q9JM47

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Anti-KChIP3 K+ Channel Antibody FL490 Conjugate (K66/38)

SKU: 75-005-FL490

Product Details

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