Anti-KChIP2b K+ Channel Antibody (K60/73)


Primary Antibody
Canine, Human, Mouse, Pig, Rat
K60/73
ChIP, ICC, IHC, IP, WB
Mouse
Purified
Kcnip2 Kchip2
35 kDa

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Anti-KChIP2b K+ Channel Antibody
SKU: 75-004

Volume: 100 µL
Price:
Sale price$295


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Product Specific References for Applications and Species

Chromatin Immunoprecipitation: Mouse
PMID Dilution Publication
310175731:50Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons. . Elife, e40818.
2734918513 ug/mlWinther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12.
Immunocytochemistry: Human
PMID Dilution Publication
2734918510.4 ug/mlWinther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12.
Immunocytochemistry: Mouse
PMID Dilution Publication
215079521:10 (supe)Cheng, L., et al. 2011. Cortactin is required for N-cadherin regulation of Kv1.5 channel function.. The Journal of Biological Chemistry, 20478-20489.
Immunocytochemistry: Rat
PMID Dilution Publication
282637091:50Nassal, D.M., et al. 2017. KChIP2 is a core transcriptional regulator of cardiac excitability. . Elife, 17304.
255517701:500Isensee, J., et al. 2014. Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit.. PLoS One, e115731.
226123221:500Pruunsild, P., et al. 2012. Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression.. Journal of Neurochemistry, 29-43.
Immunohistochemistry: Mouse
PMID Dilution Publication
360977911:50Chiu, C.Y., et al. 2022. K+ Channel Kv4.1 is Expressed in the Nociceptors/Secondary Nociceptive Neurons and Participates in Pain Regulation. European Journal of Pain, 2238-2256.
22612819not listedMenegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-149.
22612819not listedMenegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-149.
17122038not listedMenegola, M. , et al. 2006. Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain.. Journal of Neuroscience, 2137-42.
Immunohistochemistry: Rat
PMID Dilution Publication
283308771:50Kuo, Y.L., et al. 2017. K + Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.. Journal of Neuroscience, 4391-4404.
24037673not listedRainnie, D.G., et al. 2014. Distribution and functional expression of Kv4 family α subunits and associated KChIP β subunits in the bed nucleus of the stria terminalis.. Journal of Comparative Neurology, 609-25.
18727953not listedMonaghan, M.M., et al. 2008. Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy.. Neuroscience, 550-562.
Immunoprecipitation: Human
PMID Dilution Publication
20498229not listedLevy, D.I., et al. 2010. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.. The Journal of Physiology, 2657-2668.
Western Blot: Canine
PMID Dilution Publication
22820054not listedÖzgen, N., et al. 2012. Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.. Heart Rhythm, 1865-1872.
196322391:200Calloe, K., et al. 2010. Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.. Journal of Molecular and Cellular Cardiology, 191-200.
Western Blot: Human
PMID Dilution Publication
20709747not listedFoeger, N.C., et al. 2010. Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexes.. The Journal of Biological Chemistry, 33413-33422.
20498229not listedLevy, D.I., et al. 2010. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.. The Journal of Physiology, 2657-2668.
Western Blot: Mouse
PMID Dilution Publication
32822706not listedTiwari, D., et al. 2020. The potassium channel Kv4. 2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice. . Experimental Neurology, 113437.
31071333not listedEdnie, A.R., et al. 2019. Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy.. Journal of Molecular and Cellular Cardiology, 13-23.
310175731:1000Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons. . Elife, e40818.
27697822not listedKhandekar, A., et al. 2016. Notch-mediated epigenetic regulation of voltage-gated potassium currents. . Circulation Research, 1324-1338.
273491853.47 ug/mlWinther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12.
26611208not listedZhang, X., et al. 2016. Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.. Basic Research in Cardiology, 1-16.
262972291:1000Liu, W.J., et al. 2015. Manipulation of KCNE2 expression modulates action potential duration and Ito and IK in rat and mouse ventricular myocytes.. American Journal of Physiology-Heart and Circulatory Physiology, H1288-H1302.
243756411:200Lopez-Izquierdo, A., et al. 2014. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.. American Journal of Physiology-Heart and Circulatory Physiology, H747-H754.
24225951not listedMercer, R.C., et al. 2013. The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6.. The Journal of Biological Chemistry, 37241-37255.
240998013.5ug/mlSpeerschneider, T., et al. 2013. Development of heart failure is independent of K+ channel-interacting protein 2 expression.. The Journal of Physiology, 5923-5937.
23713033not listedFoeger, N.C., et al. 2013. Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.. The Journal of Physiology, 4149-4166.
22539834not listedMarionneau, C., et al. 2012. The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.. Journal of Neuroscience, 5716-5727.
22514734not listedSuzuki, T., et al. 2012. Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.. PLoS One, e35353.
219436061:500Sun, W., et al. 2011. DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons.. Neuron, 1102-15.
21646717not listedStein, A.B., et al. 2011. Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.. Journal of Clinical Investigation, 2641-2650.
21507952not listedCheng, L., et al. 2011. Cortactin is required for N-cadherin regulation of Kv1.5 channel function.. The Journal of Biological Chemistry, 20478-20489.
20974681not listedYang, K.C., et al. 2010. Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy.. The Journal of Physiology, 5015-5032.
20943905not listedNorris, A.J., et al. 2010. Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.. Journal of Neuroscience, 13644-13655.
192236001:1000Alexander, J.C., et al. 2009. The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.. Learning & Memory, 167-77.
192236001:1000Alexander, J.C., et al. 2009. The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.. Learning & Memory, 167-77.
18482733not listedMarionneau, C., et al. 2008. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.. Journal of Molecular and Cellular Cardiology, 1002-1015.
18451341not listedMarionneau, C., et al. 2008. Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.. Circulation Research, 1406-1415.
18045613not listedNiwa, N., et al. 2008. Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.. Journal of Molecular and Cellular Cardiology, 95-104.
Western Blot: Rabbit
PMID Dilution Publication
20405051not listedXu, X., et al. 2010. Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.. PLoS One, e10140.
Western Blot: Rat
PMID Dilution Publication
283308771:400Kuo, Y.L., et al. 2017. K + Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.. Journal of Neuroscience, 4391-4404.
282637091:50Nassal, D.M., et al. 2017. KChIP2 is a core transcriptional regulator of cardiac excitability. . Elife, 17304.
272590671:1000Lei, Z., et al. 2016. Reduced expression of IA channels is associated with post-ischemic seizures. . Epilepsy Research, 40-48.
262972291:1000Liu, W.J., et al. 2015. Manipulation of KCNE2 expression modulates action potential duration and Ito and IK in rat and mouse ventricular myocytes.. American Journal of Physiology-Heart and Circulatory Physiology, H1288-H1302.
260169051:2000You, T., et al. 2015. Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.. International Journal of Molecular Medicine, 309-315.
22367544not listedJeyaraj, D., et al. 2012. Circadian rhythms govern cardiac repolarization and arrhythmogenesis.. Nature, 96-99.
208499291:1000Dabrowska, J. , et al. 2010. Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.. Neuroscience, 721-33.
19372218not listedJiang, M., et al. 2009. Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2.. The Journal of Biological Chemistry, 16452-16462.
Western Blot: Swine
PMID Dilution Publication
24376615not listedKant, R., et al. 2013. NHE isoform switching and KChIP2 upregulation in aging porcine atria.. PLoS One, e82951.
Additional Publications: Unspecified
PMID Publication
26239200Cheng, C.F., et al. 2016. Coexpression of auxiliary subunits KChIP and DPPL in potassium channel Kv4-positive nociceptors and pain-modulating spinal interneurons.. Journal of Comparative Neurology, 846-873.
26205295El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94.
24793047Rudakova, E., et al. 2015. Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes.. Pflügers Archiv: European Journal of Physiology, 299-309.
25043828Lei, Z., et al. 2014. Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats.. Journal of Neuroscience Research, 1775-1784.
21129448Bourdeau, M.L., et al. 2011. KChIP1 modulation of Kv4.3-mediated A-type K(+) currents and repetitive firing in hippocampal interneurons.. Neuroscience, 173-187.
20483361Liu, W., et al. 2010. High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins.. Journal of Molecular and Cellular Cardiology, 438-448.
20154682Anderson, D., et al. 2010. Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes.. Nature Neuroscience, 333-337.
19953263Wagner, M., et al. 2010. Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.. Pflügers Archiv: European Journal of Physiology, 607-618.
19768467Soltysinska, E., et al. 2009. Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.. Pflügers Archiv: European Journal of Physiology, 11-23.

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