Anti-KChIP2b K+ Channel Antibody (K60/73)
Primary Antibody
Human, Mouse, Rat
K60/73
IHC, IP, WB
Mouse
Purified
Kcnip2 Kchip2
35 kDa
Adult rat hippocampus immunohistochemistry.
- Zhang X, Ai X, Nakayama H, Chen B, Harris DM, Tang M, Xie Y, Szeto C, Li Y, Li Y, Zhang H, Eckhart AD, Koch WJ, Molkentin JD, Chen X, (2016), 'Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias..' Basic Research in Cardiology. 10.1007/s00395-015-0523-4.
- Cheng CF, Wang WC, Huang CY, Du PH, Yang JH, Tsaur ML. (2016), 'Coexpression of auxiliary subunits KChIP and DPPL in potassium channel Kv4-positive nociceptors and pain-modulating spinal interneurons..' Journal of Comparative Neurology. 10.1002/cne.23876.
- Liu WJ, Deng JX, Wang G, Gao KP, Lin ZX, Liu SY, Wang YH, Liu J. (2015), 'Manipulation of KCNE2 expression modulates action potential duration and Ito and IK in rat and mouse ventricular myocytes..' American Journal of Physiology-Heart and Circulatory Physiology. 10.1152/ajpheart.00757.2014.
- El Gebeily G, El Khoury N, Mathieu S, Brouillette J, Fiset C. (2015), 'Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart..' Journal of Molecular and Cellular Cardiology. 10.1016/j.yjmcc.2015.07.013.
- You T, Mao W, Cai B, Li F, Xu H. (2015), 'Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function..' International Journal of Molecular Medicine. 10.3892/ijmm.2015.2223.
- Rudakova E, Wagner M, Frank M, Volk T. (2015), 'Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes..' Pflügers Archiv: European Journal of Physiology. 10.1007/s00424-014-1521-3.
- Isensee J, Wenzel C, Buschow R, Weissmann R, Kuss AW, Hucho T. (2014), 'Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit..' PLoS One. 10.1371/journal.pone.0115731.
- Lei Z, Zhang H, Liang Y, Cui Q, Xu Z, Xu ZC. (2014), 'Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats..' Journal of Neuroscience Research. 10.1002/jnr.23445.
- Lopez-Izquierdo A, Pereira RO, Wende AR, Punske BB, Abel ED, Tristani-Firouzi M. (2014), 'The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization..' American Journal of Physiology-Heart and Circulatory Physiology. 10.1152/ajpheart.00849.2013.
- Rainnie DG, Hazra R, Dabrowska J, Guo JD, Li CC, Dewitt S, Muly EC. (2014), 'Distribution and functional expression of Kv4 family α subunits and associated KChIP β subunits in the bed nucleus of the stria terminalis..' Journal of Comparative Neurology. 10.1002/cne.23435.
- Kant R, Hu Z, Malhotra JK, Krogh-Madsen T, Christini DJ, Heerdt PM, Abbott GW. (2013), 'NHE isoform switching and KChIP2 upregulation in aging porcine atria..' PLoS One. 10.1371/journal.pone.0082951.
- Mercer RC, Ma L, Watts JC, Strome R, Wohlgemuth S, Yang J, Cashman NR, Coulthart MB, Schmitt-Ulms G, Jhamandas JH, Westaway D. (2013), 'The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6..' The Journal of Biological Chemistry. 10.1074/jbc.M113.488650.
- Speerschneider T, Grubb S, Metoska A, Olesen SP, Calloe K, Thomsen MB. (2013), 'Development of heart failure is independent of K+ channel-interacting protein 2 expression..' The Journal of Physiology. 10.1113/jphysiol.2013.263483.
- Foeger NC, Wang W, Mellor RL, Nerbonne JM. (2013), 'Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents..' The Journal of Physiology. 10.1113/jphysiol.2013.255836.
- Özgen N, Lu Z, Boink GJ, Lau DH, Shlapakova IN, Bobkov Y, Danilo P Jr, Cohen IS, Rosen MR. (2012), 'Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing..' Heart Rhythm. 10.1016/j.hrthm.2012.07.014.
- Menegola M, Clark E, Trimmer JS. (2012), 'The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice..' Epilepsia. 10.1111/j.1528-1167.2012.03485.x.
- Pruunsild P, Timmusk T. (2012), 'Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression..' Journal of Neurochemistry. 10.1111/j.1471-4159.2012.07796.x.
- Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM. (2012), 'The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels..' Journal of Neuroscience. 10.1523/JNEUROSCI.6450-11.2012.
- Suzuki T, Shioya T, Murayama T, Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H, Morimoto S, Kurebayashi N. (2012), 'Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy..' PLoS One. 10.1371/journal.pone.0035353.
- Jeyaraj D, Haldar SM, Wan X, McCauley MD, Ripperger JA, Hu K, Lu Y, Eapen BL, Sharma N, Ficker E, Cutler MJ, Gulick J, Sanbe A, Robbins J, Demolombe S, Kondratov RV, Shea SA, Albrecht U, Wehrens XH, Rosenbaum DS, Jain MK. (2012), 'Circadian rhythms govern cardiac repolarization and arrhythmogenesis..' Nature. 10.1038/nature10852.
- Marshall GE, Russell JA, Tellez JO, Jhund PS, Currie S, Dempster J, Boyett MR, Kane KA, Rankin AC, Workman AJ. (2011), 'Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade..' Pflügers Archiv: European Journal of Physiology. 10.1007/s00424-011-1061-z.
- Sun W, Maffie JK, Lin L, Petralia RS, Rudy B, Hoffman DA. (2011), 'DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons..' Neuron. 10.1016/j.neuron.2011.08.008.
- Stein AB, Jones TA, Herron TJ, Patel SR, Day SM, Noujaim SF, Milstein ML, Klos M, Furspan PB, Jalife J, Dressler GR. (2011), 'Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes..' Journal of Clinical Investigation. 10.1172/JCI44641.
- Cheng L, Yung A, Covarrubias M, Radice GL. (2011), 'Cortactin is required for N-cadherin regulation of Kv1.5 channel function..' The Journal of Biological Chemistry. 10.1074/jbc.M111.218560.
- Bourdeau ML, Laplante I, Laurent CE, Lacaille JC. (2011), 'KChIP1 modulation of Kv4.3-mediated A-type K(+) currents and repetitive firing in hippocampal interneurons..' Neuroscience. 10.1016/j.neuroscience.2010.11.051.
- Yang KC, Foeger NC, Marionneau C, Jay PY, McMullen JR, Nerbonne JM. (2010), 'Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy..' The Journal of Physiology. 10.1113/jphysiol.2010.197418.
- Norris AJ, Foeger NC, Nerbonne JM. (2010), 'Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons..' Journal of Neuroscience. 10.1523/JNEUROSCI.2487-10.2010.
- Dabrowska J, Rainnie DG. (2010), 'Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala..' Neuroscience. 10.1016/j.neuroscience.2010.09.011.
- Foeger NC, Marionneau C, Nerbonne JM. (2010), 'Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexes..' The Journal of Biological Chemistry. 10.1074/jbc.M110.145185.
- Levy DI, Cepaitis E, Wanderling S, Toth PT, Archer SL, Goldstein SA. (2010), 'The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner..' The Journal of Physiology. 10.1113/jphysiol.2010.191395.
- Liu W, Deng J, Xu J, Wang H, Yuan M, Liu N, Jiang Y, Liu J. (2010), 'High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins..' Journal of Molecular and Cellular Cardiology. 10.1016/j.yjmcc.2010.05.004.
- Xu X, Jiang M, Wang Y, Smith T, Baumgarten CM, Wood MA, Tseng GN. (2010), 'Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model..' PLoS One. 10.1371/journal.pone.0010140.
- Anderson D, Mehaffey WH, Iftinca M, Rehak R, Engbers JD, Hameed S, Zamponi GW, Turner RW. (2010), 'Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes..' Nature Neuroscience. 10.1038/nn.2493.
- Wagner M, Rudakova E, Schütz V, Frank M, Ehmke H, Volk T. (2010), 'Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice..' Pflügers Archiv: European Journal of Physiology. 10.1007/s00424-009-0762-z.
- Calloe K, Soltysinska E, Jespersen T, Lundby A, Antzelevitch C, Olesen SP, Cordeiro JM. (2010), 'Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle..' Journal of Molecular and Cellular Cardiology. 10.1016/j.yjmcc.2009.07.017.
- Soltysinska E, Olesen SP, Christ T, Wettwer E, Varró A, Grunnet M, Jespersen T. (2009), 'Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts..' Pflügers Archiv: European Journal of Physiology. 10.1007/s00424-009-0718-3.
- Jiang M, Xu X, Wang Y, Toyoda F, Liu XS, Zhang M, Robinson RB, Tseng GN. (2009), 'Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2..' The Journal of Biological Chemistry. 10.1074/jbc.M808262200.
- Alexander JC, McDermott CM, Tunur T, Rands V, Stelly C, Karhson D, Bowlby MR, An WF, Sweatt JD, Schrader LA. (2009), 'The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning..' Learning & Memory. 10.1101/lm.1261709.
- Monaghan MM, Menegola M, Vacher H, Rhodes KJ, Trimmer JS. (2008), 'Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy..' Neuroscience. 10.1016/j.neuroscience.2008.07.057.
- Marionneau C, Aimond F, Brunet S, Niwa N, Finck B, Kelly DP, Nerbonne JM. (2008), 'PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy..' Journal of Molecular and Cellular Cardiology. 10.1016/j.yjmcc.2008.03.023.
- Marionneau C, Brunet S, Flagg TP, Pilgram TK, Demolombe S, Nerbonne JM. (2008), 'Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy..' Circulation Research. 10.1161/CIRCRESAHA.107.170050.
- Niwa N, Wang W, Sha Q, Marionneau C, Nerbonne JM. (2008), 'Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles..' Journal of Molecular and Cellular Cardiology. 10.1016/j.yjmcc.2007.10.007.
- Menegola M, Trimmer JS. (2006), 'Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain..' Journal of Neuroscience. 10.1523/JNEUROSCI.2783-06.2006.