Kv Channel Interacting Protein 2, Kchip2 potassium channel subunit, or potassium channel auxiliary subunit KCHIP2b is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip2 is a calcium binding protein and an integral subunit component of native Kv4 channel complexes. Kchip2 is primarily expressed in heart tissue but is also found in brain. Diseases associated with KCNIP2 include Spinocerebellar Ataxia Type 19/22, Brugada Syndrome, long qt syndrome 1, and dilated cardiomyopathy.
IHC, IP, WB
Fusion protein amino acids 1-252 (full length) of rat KChIP2b (accession number AAF81756); Human: 96% identity (244/252 amino acids); Mouse=100% identity
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against rat KChIPs 1,3
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2)