Anti-Ionized Calcium Binding Adapter Molecule 1 (IBA1) Antibody

Name: Anti-Ionized Calcium Binding Adapter Molecule 1 (IBA1) Antibody
Brand: Biosensis
SKU: C-2118-50
Price: 327.0 USD
Availability: InStock

Our Anti-Ionized calcium binding adapter molecule 1 (IBA1) chicken polyclonal primary antibody detects human, mouse, and rat Ionized calcium binding adapter molecule 1 (IBA1), and is IgY fraction. It is validated for use in ICC, IHC-Frozen, WB.

Left:Rat spinal cordsection stained with C-2118-50 (red) and nuclear DNA (DAPI stain, blue) by Immunohistochemistry.Microglia are visualized in a confocal Z stack as they are small cells spreading in three dimensions. Right:Western blot analysis of C-2118-50 (green, 1:1000) with a band at approx. 15kDa. Lane 1: protein standard (red); Lane 2: Rat spleen homogenate.

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Chicken

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Data Sheet

SKU: C-2118-50

Volume/Size: 50 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Ionized calcium binding adapter molecule 1 (IBA1)

Scientific Background

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (Ref: uniprot.org)

Format

IgY Fraction

Clonality

Polyclonal

Isotype

IgY

Applications

ICC, IHC, WB

Host Species

Chicken

Immunogen

C-terminal peptide of human IBA1. The antibody has been made against the C-terminal peptide of human IBA1 coupled to keyhole limpet hemocyanin (KLH).

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. Store at 4°C for up to one month for short term storage and frequent use.

Physical State

Lyophilized

Buffer

Lyophilized IgY preparation, with sodium azide.

Dilution Ranges

WB: 1:5000-1:10000
IHC: 1:100-1:500
ICC: 1:100-1:500

Conjugate

Unconjugated

Specificity

Human. Species cross-reactivity includes rat and mouse.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

IBA-1; AIF1; AIF-1 G1; Allograft inflammatory factor 1; Ionized calcium binding adapter molecule 1; Protein G1

UniProt ID

P55008

Shipping

25°C (ambient)

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Anti-Ionized Calcium Binding Adapter Molecule 1 (IBA1) Antibody

SKU: C-2118-50

Product Details

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