Anti-Homer1 Antibody (L113/130)

Name: Anti-Homer1 Antibody
Brand: NeuroMab
SKU: 75-454
Price: 329.0 USD
Availability: InStock

Our Anti-Homer1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L113/130. It detects human, mouse, and rat Homer1, and is purified by Protein A chromatography. It is great for use in AT, IHC, ICC, WB.

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 2/3 with L113/130 (green), rabbit mAb PSD-95 (Cell Signaling

Adult rat hippocampus immunohistochemistry.

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 2/3 with L113/130 (green), rabbit mAb PSD-95 (Cell Signaling #3450, red) and DAPI (blue), where L113/130 colocalizes with many PSD-95 puncta. Image courtesy of Kristina Micheva (Stanford)..

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-454

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Homer1

Scientific Background

Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L113/130

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Homer1 Vesl1

Molecular Weight

50 kDa

Immunogen

Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (accession number Q9Z2Y3) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2686914

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

UniProt ID

Q9Z2Y3

Shipping

Shipped on ice packs

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Anti-Homer1 Antibody (L113/130)

SKU: 75-454

Product Details

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