Anti-Homer1 Antibody (L113/130)

Name: Anti-Homer1 Antibody
Brand: NeuroMab
SKU: 75-454
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

Homer1 Vesl1

Molecular Weight

50 kDa

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Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 2/3 with L113/130 (green), rabbit mAb PSD-95 (Cell Signaling

Adult rat hippocampus immunohistochemistry.

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 2/3 with L113/130 (green), rabbit mAb PSD-95 (Cell Signaling #3450, red) and DAPI (blue), where L113/130 colocalizes with many PSD-95 puncta. Image courtesy of Kristina Micheva (Stanford)..

Product Details

Target

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

Target Description

Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L113/130

Isotype

IgG1

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

Homer1 Vesl1

Molecular Weight

50 kDa

Antigen

Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (also known as Homer protein homolog 1, VASP/Ena-related gene up-regulated during seizure and LTP 1, Vesl-1, Vesl, SYN47 and PSD-Zip45, accession number Q9Z2Y3); Rat: 97% identity (236/243 amino acids identical); Human: 93% identity (226/243 amino acids identical); 40% identity with Homer2

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2686914

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

UniProt Details

UniProt (Human): Q86YM7
UniProt (Immunogen Species): Q9Z2Y3

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Anti-Homer1 Antibody (L113/130)

Anti-Homer1 Antibody
SKU: 75-454

Product Details

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Anti-Homer1 Antibody (L113/130)

Anti-Homer1 Antibody SKU: 75-454

Product Details

Anti-Homer1 Antibody
SKU: 75-454