Anti-Haspin/GSG2 Antibody (N128A/2)

Name: Anti-Haspin/GSG2 Antibody
Brand: NeuroMab
SKU: 75-161
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human

Clone

N128A/2

Applications

ICC, IP, WB

Host Species

Mouse

Format

Purified

Gene Name

HASPIN GSG2

Molecular Weight

90 kDa

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Transfected cell immunoblot: extracts of COS cells transfected with Myc- tagged human Haspin and untagged Kv2.1 plasmids and probed with N128A/2 (left) and K89/41 (right) tissue culture supernatant.

Transfected cell immunofluorescence: COS cells expressing Myc-tagged human Haspin. Red = rabbit anti-Myc, Green = N128A/2, Blue = Hoechst nuclear stain.

Volume: 100 µL

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Product Details

Target

Haspin/GSG2

Target Description

Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N128A/2

Isotype

IgG1

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

HASPIN GSG2

Molecular Weight

90 kDa

Antigen

Fusion protein amino acids 1-798 (full-length) of human Haspin (also known as serine/threonineprotein kinase haspin, haploid germ cell-specific nuclear protein kinase, germ cell-specific gene 2 protein and GSG2, accession number Q8TF76); Mouse: 61% identity (493/799 amino acids identical)

Species Reactivity

Human

Antibody Registry ID

AB_2114890

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

UniProt Details

UniProt (Human): Q8TF76
UniProt (Immunogen Species): Q8TF76

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Anti-Haspin/GSG2 Antibody (N128A/2)

Anti-Haspin/GSG2 Antibody
SKU: 75-161

Bulk Order Anti-Haspin/GSG2 Antibody

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Anti-Haspin/GSG2 Antibody (N128A/2)

Anti-Haspin/GSG2 Antibody SKU: 75-161

Bulk Order Anti-Haspin/GSG2 Antibody

Product Details

Anti-Haspin/GSG2 Antibody
SKU: 75-161