Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate (N59/36)

Name: Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-101-FL550
Price: 499.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N59/36

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Grin2b

Molecular Weight

166 kDa

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Volume: 200 µL

Variant

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$499

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Bulk Order Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate

Product Details

Target

GluN2B/NR2B glutamate receptor

Target Description

GluN2B/NR2b glutamate receptor, also known as Glutamate/N-methyl D-aspartate/NMDA receptor subtype 2B, is a member of the NMDA receptor family. NMDA receptors are expressed throughout the CNS in postsynaptic cell membranes. GluN2B is a major NMDAR subtype found in cortical and hippocampal regions of the adult brain. NMDA receptors are involved with memory and learning. Mutations in the gene encoding GluN2B are associated with autism, LennoxGastaut and West Syndromes.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N59/36

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Grin2b

Molecular Weight

166 kDa

Antigen

Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B (accession number Q00960) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939377

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with GluN2A/NR2A

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)

UniProt Details

UniProt (Human): Q13224
UniProt (Immunogen Species): Q00960

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Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate (N59/36)

Available Conjugates

Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate
SKU: 75-101-FL550

Bulk Order Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate

Product Details

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Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate (N59/36)

Available Conjugates

Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate SKU: 75-101-FL550

Bulk Order Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate

Product Details

Anti-GluN2B/NR2B Glutamate Receptor Antibody FL550 Conjugate
SKU: 75-101-FL550