Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Gammaprotocadherin-C4 or untagged Kv2.1 plasmid and probed with N193A/13 (left) and N86/8 (right) TC supe.
Protocadherin Gamma Subfamily C, 4 is encoded by the gene PCDHGC4. PCDHGC4 is a member of the protocadherin gamma gene cluster. PCDHGC4 is a neural cadherin-like cell adhesion protein that most likely plays a critical role in the establishment and function of specific cell-cell connections in the brain. PCDHGC4 is expressed in the nervous system, skin, and eye. No diseases were found to be associated with PCDHGC4.
Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-C4 (also known as PCDH-gamma-C4, accession number Q91XX0); Human: 98% identity (84/85 amino acids identical)
Less than 50% identity with other Gamma-protocadherin-C proteins
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against other Gamma-protocadherin-A, -B or -C proteins
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.