Immunoblot against extracts of COS cells transiently transfected with untagged GABAARPi, GFP-tagged GABAARDelta or untagged Kv2.1 plasmid probed with N431/64 (left) or N86/8 (right) TC supe.
Bulk Order Anti-GABA-A-R-Pi Antibody
Gamma-aminobutyric acid receptor subunit pi or GABA AR Pi is encoded by the gene GABRP. GABA A receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR pi is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR Pi has been found in tissues including the uterus, ovaries lung, thymus and prostate.
Purified by Protein A chromatography
ICC, IHC, WB
Fusion protein amino acids 22-242 (extracellular N-terminus) of human GABA-A receptor Pi (accession number O00591) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Does not cross-react with GABAARDelta
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Gamma-aminobutyric acid receptor subunit pi (GABA(A) receptor subunit pi)