Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7
C-fos belongs the Fos family. Other members include FosB, Fra-1, Fra-2. c-fos binds to JUN/AP1 transcription factor. C-Fos is expressed in placental tissue, fetal liver, developing bone, developing central nervous system, and adult bone marrow. It is expressed in the nucleus and in the endoplasmic reticulum. c-Fos is has a role in signal transduction, cell proliferation, differentiation, and apoptosis. C-Fos is overexpressed in many cancers.
Purified
1 mg/mL
Monoclonal
N486/32
IgG2a
ICC, IHC, WB
Mouse
FOS, G0S7
50 kDa
Fusion protein amino acids 1-377 (full-length) of human FOS (also known as Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7 and G0S7, accession number P01100); Rat: 94% identity (355/377 amino acids identical); Mouse: 94% identity (353/377 amino acids identical); <50% identity with FOSL2
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when tested by Western Blot.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7
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