Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N202/7 (left) or N52A/42 (right) TC supe.
Polyphosphoinositide phosphatase, SAC Domain-Containing Protein 3 or Fig4/Sac3 is encoded by the gene FIG4. Fig4/Sac3. The hydrolyzing phosphoinositide signals is involved with cell processes including intracellular membrane trafficking, exocytosis, endocytosis and membrane transport. Fig4/Sac3 is found widely in tissues. Diseases associated with this gene include Polymicrogyria, Yunis-Varon Syndrome and Charcot-Marie-Tooth Disease.
ICC, IHC, WB
Fig4 Kiaa0274 Sac3
Fusion protein amino acids 688-907 of mouse Sac3 (also known as SAC domain-containing protein 3, FIG4 homolog and KIAA0274, accession number Q91WF7); Rat: 95% identity (203/220 amino acids identical); Human: 91% identity (201/220 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.