Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Name: Anti-FGF13/FHF2, B Isoform Antibody
Brand: NeuroMab
SKU: 75-248
Price: 329.0 USD
Availability: InStock

1 Citation

Our Anti-FGF13/FHF2, B isoform mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N225A/10. It detects human FGF13/FHF2, B isoform, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged FGF13B/FHF2B, FGF13A/FHF2A or untagged Kv2.1 plasmid and probed with N225A/10 (left) or N86/8 (right) TC supe.

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Species Reactivity

Human

Applications

ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-248

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

FGF13/FHF2, B isoform

Scientific Background

Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N225A/10

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

FGF13 FHF2

Molecular Weight

20 kDa

Immunogen

Synthetic peptide amino acids 1-20 (MALLRKSYSEPQLKGIVTKL) of human FHF2B (accession number Q92913-2)

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_11001555

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with FGF13A/FHF2A

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)

UniProt ID

Q92913-2

Shipping

Shipped on ice packs

Product Specific References for Applications and Species

Immunocytochemistry: Rat
Western Blot: Rat

Immunocytochemistry: Rat
PMID	Dilution	Publication
27999940	1:200	Barbosa, C., et al. 2017. FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons.. Pflugers Archiv, 195-212.

Western Blot: Rat
PMID	Dilution	Publication
27999940	1:200	Barbosa, C., et al. 2017. FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons.. Pflugers Archiv, 195-212.

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Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

SKU: 75-248

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

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