Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged FGF13B/FHF2B, FGF13A/FHF2A or untagged Kv2.1 plasmid and probed with N225A/10 (left) or N86/8 (right) TC supe.
Anti-FGF13/FHF2, B Isoform Antibody
FGF13/FHF2, B isoform
Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.
Synthetic peptide amino acids 1-20 (MALLRKSYSEPQLKGIVTKL) of human FHF2B (also known as Fibroblast growth factor homologous factor 2B, Fibroblast growth factor 13B and FGF13B, accession number Q92913-2); Rat: 100% identity (20/20 amino acids identical); Mouse: 100% identity (20/20 amino acids identical) 55% identity with FGF13A/FHF2A
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with FGF13A/FHF2A
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.