Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Name: Anti-FGF13/FHF2, B Isoform Antibody
Brand: NeuroMab
SKU: 75-248
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Human

Clone

N225A/10

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

FGF13 FHF2

Molecular Weight

20 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged FGF13B/FHF2B, FGF13A/FHF2A or untagged Kv2.1 plasmid and probed with N225A/10 (left) or N86/8 (right) TC supe.

Volume: 100 µL

Variant

Price:

$295

Quantity:

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

Product Details

Target

FGF13/FHF2, B isoform

Target Description

Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N225A/10

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

FGF13 FHF2

Molecular Weight

20 kDa

Antigen

Synthetic peptide amino acids 1-20 (MALLRKSYSEPQLKGIVTKL) of human FHF2B (also known as Fibroblast growth factor homologous factor 2B, Fibroblast growth factor 13B and FGF13B, accession number Q92913-2); Rat: 100% identity (20/20 amino acids identical); Mouse: 100% identity (20/20 amino acids identical) 55% identity with FGF13A/FHF2A

Species Reactivity

Human

Antibody Registry ID

AB_11001555

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with FGF13A/FHF2A

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)

UniProt Details

UniProt (Human): Q92913
UniProt (Immunogen Species): Q92913-2

Barbosa C, Xiao Y, Johnson AJ, Xie W, Strong JA, Zhang JM, Cummins TR,. (2017), 'FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons..' Pflugers Arch.. 10.1007/s00424-016-1911-9.

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Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Anti-FGF13/FHF2, B Isoform Antibody
SKU: 75-248

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

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Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Anti-FGF13/FHF2, B Isoform Antibody SKU: 75-248

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

Product Details

Anti-FGF13/FHF2, B Isoform Antibody
SKU: 75-248