Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Name: Anti-FGF13/FHF2, B Isoform Antibody
Brand: NeuroMab
SKU: 75-248
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human

Clone

N225A/10

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

FGF13 FHF2

Molecular Weight

20 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged FGF13B/FHF2B, FGF13A/FHF2A or untagged Kv2.1 plasmid and probed with N225A/10 (left) or N86/8 (right) TC supe.

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

Product Details

Target

FGF13/FHF2, B isoform

Target Description

Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N225A/10

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

FGF13 FHF2

Molecular Weight

20 kDa

Antigen

Synthetic peptide amino acids 1-20 (MALLRKSYSEPQLKGIVTKL) of human FHF2B (accession number Q92913-2)

Species Reactivity

Human

Antibody Registry ID

AB_11001555

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with FGF13A/FHF2A

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)

UniProt Details

UniProt (Human): Q92913
UniProt (Immunogen Species): Q92913-2

Barbosa C, Xiao Y, Johnson AJ, Xie W, Strong JA, Zhang JM, Cummins TR,. (2017), 'FHF2 isoforms differentially regulate Nav1.6-mediated resurgent sodium currents in dorsal root ganglion neurons..' Pflugers Arch.. 10.1007/s00424-016-1911-9.

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Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Available Conjugates

Anti-FGF13/FHF2, B Isoform Antibody
SKU: 75-248

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

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Anti-FGF13/FHF2, B Isoform Antibody (N225A/10)

Available Conjugates

Anti-FGF13/FHF2, B Isoform Antibody SKU: 75-248

Bulk Order Anti-FGF13/FHF2, B Isoform Antibody

Product Details

Anti-FGF13/FHF2, B Isoform Antibody
SKU: 75-248