Anti-FGF12/FHF1 Antibody (N94/17)

Name: Anti-FGF12/FHF1 Antibody
Brand: NeuroMab
SKU: 75-135
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

3 Citations

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N94/17

Applications

ICC, IHC, IP

Host Species

Mouse

Format

Purified

Gene Name

FGF12 FGF12B FHF1

Molecular Weight

27 kDa

Go to Full Product Details

Transfected cell immunofluorescence: COS cells expressing GFP-tagged FGF12b/FHF1b. Red = N94/17, Green = GFP, Blue = Hoechst nuclear stain.

Volume: 100 µL

Variant

Price:

$308

Quantity:

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Product Details

Target

FGF12/FHF1

Target Description

Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N94/17

Isotype

IgG1

Applications

ICC, IHC, IP

Host Species

Mouse

Gene Name

FGF12 FGF12B FHF1

Molecular Weight

27 kDa

Antigen

Fusion protein amino acids 1-243 (full-length) of human FGF12a (also known as fibroblast growth factor homologous factor 12a or FHF1a, accession number P61328) Rat: 100% identity (243/243 amino acids identical); Mouse: 100% identity (243/243 amino acids identical); 60% identity with FGF11/FHF3, FGF13/FHF2 and FGF14/FHF4High identity with FGF12b/FHF1b

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2278408

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Cross-reacts with FGF12b/FHF1bDoes not cross-react with FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)

UniProt Details

UniProt (Human): P61328
UniProt (Immunogen Species): P61328

Product Specific References for Applications and Species

Immunocytochemistry: Human
Immunohistochemistry: Rat
Western Blot: Rat

Immunocytochemistry: Human
PMID	Dilution	Publication
35064871	1:200	Fularczyk, N., et al. 2022. A Learning Based Framework for Disease Prediction from Images of Human-Derived Pluripotent Stem Cells of Schizophrenia Patients.. Neuroinformatics, 1-11.

Immunohistochemistry: Rat
PMID	Dilution	Publication
25724910	1:100	Wildburger, N.C., et al. 2015. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain.. Molecular & Cellular Proteomics, 1288-300.

Western Blot: Rat
PMID	Dilution	Publication
25724910	1:100	Wildburger, N.C., et al. 2015. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain.. Molecular & Cellular Proteomics, 1288-300.

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Anti-FGF12/FHF1 Antibody (N94/17)

Anti-FGF12/FHF1 Antibody
SKU: 75-135

Bulk Order Anti-FGF12/FHF1 Antibody

Product Details

Product Specific References for Applications and Species

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Anti-FGF12/FHF1 Antibody (N94/17)

Anti-FGF12/FHF1 Antibody SKU: 75-135

Bulk Order Anti-FGF12/FHF1 Antibody

Product Details

Product Specific References for Applications and Species

Anti-FGF12/FHF1 Antibody
SKU: 75-135