Transfected cell immunoblot: extracts of whole rat brain homogenate (WBH) and COS cells transfected with GFP-tagged FGF11/FHF3 and FGF13/FHF2 and untagged Kv2.1 plasmids and probed with N92/14 (left) and N52A/42 (right) TC supe.
Bulk Order Anti-FGF11/FHF3 Antibody
Fibroblast growth factor 11, FHF3 or FGF11 is encoded by the gene FGF11. FHF3 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FHF3 is expressed in the Nervous system. Diseases associated with FGF11 include Congenital Myasthenic Syndrome 2A and Congenital Myasthenic Syndrome.
Purified by Protein A chromatography
ICC, IP, WB
Fusion protein amino acids 55-216 of human FGF11a (accession number Q92914) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.59
Does not cross-react with FGF12, FGF13 or FGF14 in heterologous cells
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.