Anti-FGF11/FHF3 Antibody (N92/14)

Name: Anti-FGF11/FHF3 Antibody
Brand: NeuroMab
SKU: 75-133
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse

Clone

N92/14

Applications

ICC, IP, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

FGF11 FHF3

Molecular Weight

25 kDa

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Transfected cell immunoblot: extracts of whole rat brain homogenate (WBH) and COS cells transfected with GFP-tagged FGF11/FHF3 and FGF13/FHF2 and untagged Kv2.1 plasmids and probed with N92/14 (left) and N52A/42 (right) TC supe.

Volume: 100 µL

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Product Details

Target

FGF11/FHF3

Target Description

Fibroblast growth factor 11, FHF3 or FGF11 is encoded by the gene FGF11. FHF3 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FHF3 is expressed in the Nervous system. Diseases associated with FGF11 include Congenital Myasthenic Syndrome 2A and Congenital Myasthenic Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N92/14

Isotype

IgG2b

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

FGF11 FHF3

Molecular Weight

25 kDa

Antigen

Fusion protein amino acids 55-216 of human FGF11a (accession number Q92914) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2103926

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.59

Conjugate

Unconjugated

Specificity

Does not cross-react with FGF12, FGF13 or FGF14 in heterologous cells

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3)

UniProt Details

UniProt (Human): Q92914
UniProt (Immunogen Species): Q92914

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Anti-FGF11/FHF3 Antibody (N92/14)

Available Conjugates

Anti-FGF11/FHF3 Antibody
SKU: 75-133

Bulk Order Anti-FGF11/FHF3 Antibody

Product Details

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Anti-FGF11/FHF3 Antibody (N92/14)

Available Conjugates

Anti-FGF11/FHF3 Antibody SKU: 75-133

Bulk Order Anti-FGF11/FHF3 Antibody

Product Details

Anti-FGF11/FHF3 Antibody
SKU: 75-133