Anti-Delta Opioid Receptor Antibody

Name: Anti-Delta Opioid Receptor Antibody
Brand: PhosphoSolutions
SKU: 24538
Price: 456.0 USD
Availability: InStock

Our Delta Opioid Receptor rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Delta Opioid Receptor and is antigen affinity purified. It is great for use in WB.

Western Blot of 10ug of human brain lysate (lane 1), rat brain lysate (lane 2) and mouse brain lysate (lane 3) showing specific immunolabeling of Delta Opioid Receptor.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24538

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Delta Opioid Receptor

Scientific Background

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation. The (mu) m-, delta (d) and kappa (k) opioid receptors are GPCRs of the nervous system, which control pain, stress, and addictive behaviors. The delta opioid receptor (DOR-1) is the stereoselective receptor for enkephalins and inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

OPRD1

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human DOR-1 protein

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with N-terminal region of human, mouse and rat DOR-1 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

OPRD; OPRD1; D-OR-1; DOR-1; delta opioid receptor 1; Delta-type opioid receptor; DOR1,

UniProt ID

P41143
UniProt Summary: G-protein coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

NCBI Gene ID

4985

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Anti-Delta Opioid Receptor Antibody

SKU: 24538

Product Details

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