Anti-CRG-L2 Antibody

Name: Anti-CRG-L2 Antibody
Brand: PhosphoSolutions
SKU: 24325
Price: 456.0 USD
Availability: InStock

Our CRG-L2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human CRG-L2 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24325

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

CRG-L2

Scientific Background

A novel gene, CRG-L2 (Cancer related gene-Liver 2) displays high expression in murine and human hepatocellular carcinomas (HCC). Its restricted expression in normal tissues and unique early upregulation during tumor development make CRG-L2 an excellent candidate as a new clinical marker of HCC.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

GLDN

Immunogen

Synthetic peptide corresponding to amino acids from an internal region of the human CRG-L2 protein.

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with an internal region of the human CRG-L2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

CLOM; CRG-L2; COLM collomin; CRGL2; FLJ23917; LCCS11; colmedin; UNC-112; Cancer related gene-Liver 2; gliomedin; collomin; gliomedin,; GLDN

UniProt ID

Q6ZMI3
UniProt Summary: Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

NCBI Gene ID

342035

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Anti-CRG-L2 Antibody

SKU: 24325

Product Details

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