Anti-Collybistin Antibody (L120/30)

Name: Anti-Collybistin Antibody
Brand: NeuroMab
SKU: 75-482
Price: 337.0 USD
Availability: InStock

Our mouse Collybistin monoclonal antibody from NeuroMab is produced in-house from clone L120/30. It detects mouse and rat Collybistin and is purified by Protein A chromatography. Works in IHC, ICC, ELISA.

Adult rat cerebellum immunohistochemistry.

Adult rat superior colliculus immunohistochemistry.

Adult rat cerebellum immunohistochemistry.

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-482

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Collybistin

Scientific Background

Rho guanine nucleotide exchange factor 9 or Collybistin is encoded by the gene ARHGEF9. Collybistin is a guanine nucleotide exchange factor (GEF) and is a member of the Rho-like GTPase family. Collybistin functions to cycle active GTP to inactive GDP. Collybistin is involved in microfilament regulation and clustering of some GABA receptors and It is expressed in brain at postsynaptic membranes. Diseases associated with ARHGEF9 include Early Infantile Epileptic Encephalopathy and Hyperekplexia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L120/30

Isotype

IgG1

Applications

ELISA, ICC, IHC

Host Species

Mouse

Gene Name

Arhgef9

Molecular Weight

50-60 kDa

Immunogen

Fusion protein amino acids 105-455 of rat Collybistin (accession number Q9QX73) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2722672

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

rho guanine nucleotide exchange factor 9; Collybistin; collybistin I; rac/Cdc42 guanine nucleotide exchange factor 9

UniProt ID

Q9QX73
UniProt Summary: Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.

NCBI Gene ID

66013

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Shipped on ice packs

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Anti-Collybistin Antibody (L120/30)

SKU: 75-482

Product Details

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