Anti-Collybistin Antibody (L120/12)

Name: Anti-Collybistin Antibody
Brand: NeuroMab
SKU: 75-476
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

L120/12

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Arhgef9

Molecular Weight

50-60 kDa

Go to Full Product Details

Array tomography immunofluorescence of a Lowicryl-embedded 70 nm section from adult mouse cortex with L120/12 (green), rabbit mAb GAD2 (Cell Signaling #5843, magenta) and DAPI (blue). The insert shows three consecutive sections through the synapse that is marked with a white box. Image courtesy of Kristina Micheva (Stanford)..

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-Collybistin Antibody

Product Details

Target

Collybistin

Target Description

Rho guanine nucleotide exchange factor 9 or Collybistin is encoded by the gene ARHGEF9. Collybistin is a guanine nucleotide exchange factor (GEF) and is a member of the Rho-like GTPase family. Collybistin functions to cycle active GTP to inactive GDP. Collybistin is involved in microfilament regulation and clustering of some GABA receptors and It is expressed in brain at postsynaptic membranes. Diseases associated with ARHGEF9 include Early Infantile Epileptic Encephalopathy and Hyperekplexia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L120/12

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Arhgef9

Molecular Weight

50-60 kDa

Antigen

Fusion protein amino acids 105-455 of rat Collybistin (accession number Q9QX73) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2728741

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Dilution Ranges

WB: 1:5000

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Collybistin (Rho guanine nucleotide exchange factor 9) (Rac/Cdc42 guanine nucleotide exchange factor 9)

UniProt Details

UniProt (Human): O43307
UniProt (Immunogen Species): Q9QX73

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
32202499	1:5000	Zhang, R.S., et al. 2020. Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum. Elife, e54443.

Recover password

Create my account

Anti-Collybistin Antibody (L120/12)

Available Conjugates

Anti-Collybistin Antibody
SKU: 75-476

Bulk Order Anti-Collybistin Antibody

Product Details

Product Specific References for Applications and Species

Related Products

Recently Viewed

Anti-Collybistin Antibody (L120/12)

Available Conjugates

Anti-Collybistin Antibody SKU: 75-476

Bulk Order Anti-Collybistin Antibody

Product Details

Product Specific References for Applications and Species

Anti-Collybistin Antibody
SKU: 75-476