Anti-Co-Rest/RCOR1 Antibody (K72/8)

Name: Anti-Co-Rest/RCOR1 Antibody
Brand: NeuroMab
SKU: 75-039
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

RCOR1 KIAA0071 RCOR

Molecular Weight

66-80 kDa(depending on gel system used)

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Transfected cell immunoblot. Extracts of COS-1 cells transiently transfected with human CoRest (left lane) or rat Kv2.1 (right lane) plasmids and probed with K72/8.

Transfected cell immunofluorescence: COS-1 cells expressing myc-tagged human Co-Rest. Red= K72/8, Green=anti-myc, Blue=DAPI.

Product Details

Target

Co-Rest/RCOR1

Target Description

REST Corepressor 1, CoREST or RCOR is encoded by the gene RCOR1 and is a member of the CoREST family of proteins. CoREST is a corepressor to the RE1 silencing transcription factor/neural restrictive silencing (REST) transcription factor and is part of a multiprotein complex (BHC complex) that represses transcription of neuron-specific genes in non-neuronal cells. This complex determines neural cell differentiation. CoREST is ubiquitously expressed in the nucleus of cells. Diseases associated with this gene include Huntington Disease and Loeys-Dietz Syndrome 1.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K72/8

Isotype

IgG1

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

RCOR1 KIAA0071 RCOR

Molecular Weight

66-80 kDa(depending on gel system used)

Antigen

Fusion protein amino acids 109-293 of human Co-Rest (accession number Q9UKL0) Includes ELM2 and SANT domains; Rat: 83% identity (154/185 amino acids); Mouse=96% identity (178/185 amino acids) 70% overall identity to human RCOR3

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2301051

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

REST corepressor 1 (Protein CoREST)

UniProt Details

UniProt (Human): Q9UKL0
UniProt (Immunogen Species): Q9UKL0

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Anti-Co-Rest/RCOR1 Antibody (K72/8)

Anti-Co-Rest/RCOR1 Antibody
SKU: 75-039

Product Details

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Anti-Co-Rest/RCOR1 Antibody (K72/8)

Anti-Co-Rest/RCOR1 Antibody SKU: 75-039

Product Details

Anti-Co-Rest/RCOR1 Antibody
SKU: 75-039