Our Anti-CNP (2,3-cyclic nucleotide-3-phosphodiesterase) Antibody primary antibody from PhosphoSolutions is goat polyclonal. It detects bovine, human, mouse, and rat CNP (2,3-cyclic nucleotide-3-phosphodiesterase) and is affinity purified. It is great for use in WB, IHC.
Immunostaining of mouse striatum showing specific labeling of CNP in myelinating oligodendrocytes (Cat. # 326-CNP, green, 1:3000) and neurofilament L (red, 1:5000). The blue is staining DNA.
2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution (Bifulco et al., 2002). It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment (Bifulco et al., 2002, Esposito et al., 2008).
Affinity Purified
Polyclonal
IgG
IHC, WB
Goat
CNP
46 kDa
Full length human recombinant protein
Bovine, Human, Mouse, Pig, Rat
AB_ 2905460
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Liquid
Affinity purified goat serum
PBS + 50% glycerol and 5 mM NaN3
WB: 1:5000
WB Brain: 1:5000
IHC: 1:3000
Unconjugated
Specific for endogenous levels of the ~46 kDa CNP protein
Western blots performed on each lot
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
